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| Status |
Public on Dec 06, 2023 |
| Title |
Next Generation Sequencing Facilitates Quantitative Analysis of THP-1 cells under different stimulas. |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To explore the role of human RNase1 on macrophage polarization, we induced human monocytes (THP-1) to differentiate into uncommitted macrophages and then polarized them to different phenotypes by lipopolysaccharide (LPS)/interferon (IFN)-γ, interleukin (IL)-4, or RNase1 as a stimulus.
We then performed gene expression profiling analysis using data obtained from RNA-seq of Nivolumab reponders and non-reponsers.
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| |
|
| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for THP-1 cells under INF-γ plus LPS, IL-4 or RNase1 treatment.
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| |
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| Contributor(s) |
Liu C, Zhou C, Hung M |
| Citation(s) |
38307859 |
| |
| Submission date |
Oct 07, 2022 |
| Last update date |
Feb 15, 2024 |
| Contact name |
Chunxiao Liu |
| E-mail(s) |
liuchunxiao_1989@126.com
|
| Phone |
5713763441
|
| Organization name |
MD Anderson Cancer center
|
| Street address |
6565 MD Anderson Blvd., Zayed building. Z11.4000A
|
| City |
HOUSTON |
| State/province |
Texas |
| ZIP/Postal code |
77030 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
|
| Samples (8)
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| This SubSeries is part of SuperSeries: |
| GSE215013 |
Tumor samples from HCC patients receiving Nivolumab; THP-1 cells under different stimulas. |
|
| Relations |
| BioProject |
PRJNA906101 |
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