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| Status |
Public on Sep 01, 2010 |
| Title |
Gene expression analysis of cardiomyocytes treated with a clinically relevant concentration of DEHP (50 ug/mL) |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
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| Summary |
We used microarrays to expression profile cardiomyocytes from neonatal Sprague-Dawley rats treated with 50 ug/mL DEHP and control (0.1% DMSO) to identify changes in gene expression related to connexin-43 expression, calcium handling, arrhythmogenesis and mechanical motion.
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| Overall design |
Rat neonatal cardiomyocytes were treated with DEHP (diluted in 0.1% DMSO) for 3 days, control samples were treated with 0.1% DMSO. Cardiomyocytes used in the experiments were from the same litter. Samples within a treatment group (control, DEHP) are biological replicates.
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| Contributor(s) |
Posnack N, Lee N, Sarvazyan N |
| Citation(s) |
20920545 |
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| Submission date |
May 03, 2010 |
| Last update date |
Nov 06, 2013 |
| Contact name |
Nikki Gillum Posnack |
| E-mail(s) |
nposnack@childrensnational.org
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| Phone |
202-4762475
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| Organization name |
Childrens National Hospital
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| Lab |
Posnack
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| Street address |
111 Michigan Ave, NW
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| City |
Washington |
| State/province |
Please select a region, state or province. |
| ZIP/Postal code |
20010 |
| Country |
USA |
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| Platforms (1) |
| GPL6247 |
[RaGene-1_0-st] Affymetrix Rat Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (12)
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| This SubSeries is part of SuperSeries: |
| GSE21642 |
Genome-wide gene expression analysis of Di-(2-ethyl hexyl) phthalate-treated cardiomyocytes |
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| Relations |
| BioProject |
PRJNA129299 |
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