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| Status |
Public on Mar 19, 2023 |
| Title |
Transcription profiling of Smarce1- AID mESCs , cultured the cells with IAA treatment from 0min to 7 days. |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To evaluate the effects of degradation of SMARCE1 upon gene expression, we performed RNA-sequencing (RNA-seq) of cultures of two Smarce1-AID mESCs. We found that transcription of the core pluripotency regulatory network was disrupted starting from 240min and there is an accumulation till day 7 .
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| Overall design |
We performed RNA-seq in two Smarce1-AID clones mESCs in time course manner.
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| Contributor(s) |
ZHU Z, CHEN X |
| Citation(s) |
37225980 |
| Submission date |
Oct 26, 2022 |
| Last update date |
Jun 02, 2023 |
| Contact name |
Zhexin Zhu |
| E-mail(s) |
zhexin.zhu@gmail.com
|
| Organization name |
St Jude Children's Research Hospital
|
| Street address |
262 Danny Thomas Pl
|
| City |
Memphis |
| ZIP/Postal code |
38105 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (16)
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| This SubSeries is part of SuperSeries: |
| GSE189563 |
Mitotic bookmarking by SWI/SNF subunits |
|
| Relations |
| BioProject |
PRJNA894698 |
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