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GEO help: Mouse over screen elements for information. |
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Status |
Public on Jan 29, 2023 |
Title |
Spatial epigenome-transcriptome co-profiling of mammalian tissues [spatial CUT&Tag] |
Organism |
Mus musculus |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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Summary |
We present spatially resolved high-spatial-resolution genome-wide co-mapping of epigenome and transcriptome by simultaneously profiling of chromatin accessibility and gene expression (spatial-ATAC-RNA-seq), as well as histone modification and gene expression (spatial-CUT&Tag-RNA-seq) on the same tissue section at cellular level by combining the microfluidic deterministic barcoding strategy in DBiT-seq and the chemistry used in ATAC-seq/CUT&Tag.
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Overall design |
Spatially resolved co-sequencing of epigenome and transcriptome in mouse brains.
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Contributor(s) |
Fan R, Zhang D |
Citation(s) |
36922587 |
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Submission date |
Nov 02, 2022 |
Last update date |
Apr 14, 2023 |
Contact name |
Di Zhang |
E-mail(s) |
di.zhang@yale.edu
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Organization name |
Yale University
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Street address |
55 Prospect St
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City |
New Haven |
ZIP/Postal code |
06511 |
Country |
USA |
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Platforms (1) |
GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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Samples (4)
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This SubSeries is part of SuperSeries: |
GSE205055 |
Spatial epigenome-transcriptome co-profiling of mammalian tissues |
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Relations |
BioProject |
PRJNA896927 |
Supplementary file |
Size |
Download |
File type/resource |
GSE217091_RAW.tar |
2.6 Gb |
(http)(custom) |
TAR (of TSV) |
SRA Run Selector |
Raw data are available in SRA |
Processed data provided as supplementary file |
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