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Status |
Public on May 17, 2023 |
Title |
Effect of small M. tuberculosis RNA MTS1338 on the transcriptome under various stress conditions |
Organism |
Mycobacterium tuberculosis |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
The study was carried out to study the effect of small RNA MTS1338 on the M. tuberculosis transcriptome under various stress conditions (low pH, oxidative and nitrosative stress) .
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Overall design |
Control ("Empty" pMV vector, pMV_E) and overexpressing MTS1338 (1338over) strains of M. tuberculosis were grown to a logarithmic growth stage, then treated with stress conditions according to the described protocol. All experiments were performed in biological triplicates
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Contributor(s) |
Grigorov A, Albina O, Salina EG, Bychenko O, Skvortsova Y, Azhikina T |
Citation(s) |
37175635 |
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Submission date |
Nov 18, 2022 |
Last update date |
May 19, 2023 |
Contact name |
Artem Grigorov |
E-mail(s) |
artgrigorov@gmail.com
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Organization name |
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry
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Department |
Genomics and Postgenomic Technologies
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Lab |
Regulatory Transcriptomics
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Street address |
Ulitsa Miklukho-Maklaya, 16/10
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City |
Moscow |
ZIP/Postal code |
117997 |
Country |
Russia |
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Platforms (1) |
GPL27507 |
Illumina NovaSeq 6000 (Mycobacterium tuberculosis) |
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Samples (24)
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GSM6742815 |
1338over, DETA/NO, replicate 1 |
GSM6742816 |
1338over, DETA/NO, replicate 2 |
GSM6742817 |
1338over, DETA/NO, replicate 3 |
GSM6742818 |
1338over, H2O2, replicate 1 |
GSM6742819 |
1338over, H2O2, replicate 2 |
GSM6742820 |
1338over, H2O2, replicate 3 |
GSM6742821 |
1338over, pH, replicate 1 |
GSM6742822 |
1338over, pH, replicate 2 |
GSM6742823 |
1338over, pH, replicate 3 |
GSM6742824 |
pMV_E, control, replicate 1 |
GSM6742825 |
pMV_E, control, replicate 2 |
GSM6742826 |
pMV_E, control, replicate 3 |
GSM6742827 |
pMV_E, DETA/NO, replicate 1 |
GSM6742828 |
pMV_E, DETA/NO, replicate 2 |
GSM6742829 |
pMV_E, DETA/NO, replicate 3 |
GSM6742830 |
pMV_E, H2O2, replicate 1 |
GSM6742831 |
pMV_E, H2O2, replicate 2 |
GSM6742832 |
pMV_E, H2O2, replicate 3 |
GSM6742833 |
pMV_E, pH, replicate 1 |
GSM6742834 |
pMV_E, pH, replicate 2 |
GSM6742835 |
pMV_E, pH, replicate 3 |
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Relations |
BioProject |
PRJNA903197 |
Supplementary file |
Size |
Download |
File type/resource |
GSE218354_RAW.tar |
490.0 Kb |
(http)(custom) |
TAR (of CSV) |
GSE218354_counts_all.csv.gz |
212.0 Kb |
(ftp)(http) |
CSV |
SRA Run Selector |
Raw data are available in SRA |
Processed data provided as supplementary file |
Processed data are available on Series record |
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