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Series GSE218489 Query DataSets for GSE218489
Status Public on Feb 20, 2023
Title Genome-wide CRISPR/Cas9 Screens Reveal Shared and Bespoke Mechanisms of Resistance to SHP2 inhibition [CRISPR mini screen]
Organism Homo sapiens
Experiment type Other
Summary CRISPR/Cas9 screens identified unexpected hits in human AML cell lines whose loss of function causes resistance to SHP2 inhibition
 
Overall design CRISPR mini-screens were conducted with 14 cancer cell lines with a focused CRISPR library, to identify common resistant hits to SHP099
 
Contributor(s) Wei W, Neel BG
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Submission date Nov 21, 2022
Last update date Feb 20, 2023
Contact name Igor Dolgalev
Organization name NYU Grossman School of Medicine
Street address 550 1st Ave
City New York
State/province New York
ZIP/Postal code 10016
Country USA
 
Platforms (2)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
GPL30173 NextSeq 2000 (Homo sapiens)
Samples (84)
GSM6746074 Mini_screen_BV173_end_099_rep1
GSM6746075 Mini_screen_BV173_end_099_rep2
GSM6746076 Mini_screen_BV173_end_DMSO_rep1
This SubSeries is part of SuperSeries:
GSE218491 Genome-wide CRISPR/Cas9 Screens Reveal Shared and Bespoke Mechanisms of Resistance to SHP2 Inhibition
Relations
BioProject PRJNA903929

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE218489_counts-mini.txt.gz 34.6 Kb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record
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