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| Status |
Public on Feb 01, 2023 |
| Title |
Gene Expression Changes in Therapeutic Ultrasound-Treated Human Chronic Wound Tissue |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
The purpose of this study was to evaluate gene expression differences in debrided human venous ulcer tissue from patients treated with low-frequency (20 kHz), low-intensity (100 mW/cm2) ultrasound compared to a sham treatment in an effort to better understand the potential biological mechanisms.
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| Overall design |
Debrided venous ulcer tissue was collected from 32 subjects one week after sham treatment or low-frequency, low-intensity ultrasound treatment. Of these samples, 7 samples (3 ultrasound treated and 4 sham treated) yielded sufficient quality total RNA for analysis by ultra-high multiplexed PCR (Ampliseq) and expression of more than 24,000 genes was analyzed.
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| Web link |
https://pubmed.ncbi.nlm.nih.gov/37064037/
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| |
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| Contributor(s) |
Olivia B, Zahidur A, Rose D, Michael W, Michael N, Peter L, Kara S |
| Citation(s) |
37064037 |
| |
| Submission date |
Jan 09, 2023 |
| Last update date |
May 04, 2023 |
| Contact name |
Olivia Boerman |
| E-mail(s) |
ob003@bucknell.edu
|
| Phone |
570-577-1881
|
| Organization name |
Bucknell University
|
| Department |
Biomedical Engineering
|
| Street address |
One Dent Drive
|
| City |
Lewisburg |
| State/province |
PA |
| ZIP/Postal code |
17837 |
| Country |
USA |
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| Platforms (1) |
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| Samples (7)
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| Relations |
| BioProject |
PRJNA922220 |
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