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| Status |
Public on Jan 01, 2024 |
| Title |
Environmentally relevant concentrations of niclosamide disrupt antioxidant defense, histology, and the liver and intestine transcriptome of Chinese soft-shelled turtle |
| Organism |
Pelodiscus sinensis |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
To investigate the cellular responses of the Chinese soft-shelled turtle after niclosamide exposure, a total of 45 healthy juvenile turtles randomly selected and divided into three groups containing one control group (without NIC exposure, CG) and two experimental groups (exposed to 10 and 50 μg/L of NIC, respectively).
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| Overall design |
The expression profiling analysis of turtle liver and gut for after niclosmaide exposure
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| Contributor(s) |
Wu H |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Feb 20, 2023 |
| Last update date |
Jan 01, 2024 |
| Contact name |
Hao Wu |
| E-mail(s) |
wh17380133463@126.com
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| Phone |
+8617380133463
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| Organization name |
Hunan Fisheries Science Institute
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| Street address |
Shuanghe Road 728, Kaifu District, Changsha
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| City |
Changsha |
| ZIP/Postal code |
410153 |
| Country |
China |
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| Platforms (1) |
| GPL33144 |
Illumina NovaSeq 6000 (Pelodiscus sinensis) |
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| Samples (18)
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| GSM7051645 |
liver, 10 μg/L NIC exposure group, rep1 |
| GSM7051646 |
liver, 10 μg/L NIC exposure group, rep2 |
| GSM7051647 |
liver, 10 μg/L NIC exposure group, rep3 |
| GSM7051648 |
liver, 50 μg/L NIC exposure group, rep1 |
| GSM7051649 |
liver, 50 μg/L NIC exposure group, rep2 |
| GSM7051650 |
liver, 50 μg/L NIC exposure group, rep3 |
| GSM7051651 |
gut, control group, rep1 |
| GSM7051652 |
gut, control group, rep2 |
| GSM7051653 |
gut, control group, rep3 |
| GSM7051654 |
gut, 10 μg/L NIC exposure group, rep1 |
| GSM7051655 |
gut, 10 μg/L NIC exposure group, rep2 |
| GSM7051656 |
gut, 10 μg/L NIC exposure group, rep3 |
| GSM7051657 |
gut, 50 μg/L NIC exposure group, rep1 |
| GSM7051658 |
gut, 50 μg/L NIC exposure group, rep2 |
| GSM7051659 |
gut, 50 μg/L NIC exposure group, rep3 |
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| Relations |
| BioProject |
PRJNA936854 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE225631_gene_fpkm_all_samples.txt.gz |
1.5 Mb |
(ftp)(http) |
TXT |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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