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| Status |
Public on Aug 01, 2011 |
| Title |
Expression data from CD71+ cells from the bone marrow of WT, CD70TG, IFNg-/- and CD70TG*IFNg-/- mice. |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
CD70TG mice are a model for sterile chronic immune activation and develop Anemia of Inflammation, which is dependent on the production of Ifng by effector CD4 and CD8 T cells.
We used microarrays to identify Ifng-dependent differentially expressed genes that could account for the erythropoietic defect.
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| Overall design |
CD71+ cells were MACS-enriched from the bone marrow of WT, CD70TG, IFNg-/- and CD70TG*IFNg-/- male mice of 10-12 weeks of age (3 mice per genotype group).
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| Contributor(s) |
Nolte MA, Gutiérrez L |
| Citation(s) |
21725055 |
| Submission date |
Jul 01, 2010 |
| Last update date |
Mar 04, 2019 |
| Contact name |
Laura Gutierrez |
| E-mail(s) |
l.gutierrez@sanquin.nl
|
| Organization name |
Sanquin Research
|
| Department |
Blood Cell Research
|
| Street address |
Plesmanlaan 125
|
| City |
Amsterdam |
| ZIP/Postal code |
1066CX |
| Country |
Netherlands |
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| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA128025 |
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