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Series GSE227021 Query DataSets for GSE227021
Status Public on Mar 12, 2023
Title miRNA profiling in human nonsteatotic and NAFLD livers
Organism Homo sapiens
Experiment type Non-coding RNA profiling by high throughput sequencing
Summary To investigate the function of miRNAs in liver, we obtained liver tissues from nonsteatotic individuals and fatty livers from patients with nonalcoholic fatty liver disease (NAFLD). Patients due to excessive alcohol consumption, autoimmune liver disease, viral hepatitis and diabetes were excluded. Nonsteatotic livers were collected from the normal region of the livers from donors who received liver resection due to liver hemangioma, and were defined as those with NASH activity scores of 0 We then performed miRNA sequencing using livers from two NAFLD patients and two nonsteatotic individuals.
 
Overall design Comparative miRNA level profiling analysis of liver tissues from human non-steatotic and NAFLD livers.
 
Contributor(s) Liang S
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Submission date Mar 09, 2023
Last update date Mar 12, 2023
Contact name Sijia Liang
E-mail(s) liangsj5@mail.sysu.edu.cn
Organization name Sun Yat-Sen University
Department Pharmacology
Lab Cardiac and Cerebral Vascular Research Center
Street address 74 Zhongshan 2 Rd
City Guangzhou
ZIP/Postal code 510080
Country China
 
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (4)
GSM7090105 non-steatosis_rep1
GSM7090106 non-steatosis_rep2
GSM7090107 NAFLD_rep1
Relations
BioProject PRJNA942921

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE227021_processed_data.xlsx 128.7 Kb (ftp)(http) XLSX
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Raw data are available in SRA
Processed data are available on Series record

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