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| Status |
Public on Mar 12, 2023 |
| Title |
The role of miR-99a-5p in the immune regulation of host macrophages infected by Mycobacterium tuberculosis |
| Organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by high throughput sequencing
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| Summary |
This study aims to identify the specific miRNA of mycobacterium tuberculosis (M.tb) infected THP-1 by next-generation sequencing, and further to explore the role of miRNA in innate immunity against M.tb infection.Comprehensive analysis of the next-generation sequencing results showed that the expression of miR-99a-5p was significantly lower in the MTB infected THP-1 cells.
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| Overall design |
The miRNA expression profile in THP-1 cells with or without M.tb (H37Rv) infection was detected using Illumina HiSeq2500 next-generation sequencing platform.
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| Contributor(s) |
Shi Y, Pan L |
| Citation missing |
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| Submission date |
Mar 09, 2023 |
| Last update date |
Mar 14, 2023 |
| Contact name |
Yuting Shi |
| E-mail(s) |
shiyuting626@126.com
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| Phone |
15765304374
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| Organization name |
Beijing Chest Hospital, Capital Medical University
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| Street address |
No. 97 Ma Chang, Tongzhou District,Beijing of China
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| City |
Bei Jing |
| ZIP/Postal code |
101149 |
| Country |
China |
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| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA942973 |
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