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| Status |
Public on May 11, 2023 |
| Title |
Early differentially expressed immunological genes in mild and severe COVID-19 |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
We retrospectively analysed the expression of 579 immunological genes in 60 COVID-19 subjects (SARS +ve) and 59 COVID-negative (SARS -ve) subjects using the NanoString nCounter (Immunology panel), a technology based on multiplexed single-molecule counting. Biobanked Human peripheral blood mononuclear cells (PBMCs) samples underwent Nucleic Acid extraction and digital detection of mRNA to evaluate changes in antiviral gene expression between SARS -ve controls and patients with mild (SARS +ve Mild) and moderate/severe (SARS +ve Mod/Sev) disease.
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| |
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| Overall design |
119 samples (60 SARS-CoV-2 positive / 59 SARS-CoV-2 negative)
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| |
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| Contributor(s) |
Gonzalez G, MacCann R, Garcia AA |
| Citation(s) |
37261339 |
| |
| Submission date |
Mar 10, 2023 |
| Last update date |
Aug 30, 2023 |
| Contact name |
Gabriel Gonzalez |
| E-mail(s) |
gabo.gonzalez@ucd.ie
|
| Phone |
017164401
|
| Organization name |
University College Dublin
|
| Street address |
Belfield campus
|
| City |
Dublin 4 |
| State/province |
Co. Dublin |
| ZIP/Postal code |
D04V1W8 |
| Country |
Ireland |
| |
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| Platforms (1) |
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| Samples (119)
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| Relations |
| BioProject |
PRJNA943190 |
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