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| Status |
Public on Oct 06, 2023 |
| Title |
The Transcription Factor IRF4 Determines the Anti-Tumor Immunity of CD8+ T cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Four TIL populations from B16-F10 melanoma were analyzed by scRNA-seq, including adoptively transterred anti-tumor CD8+ Pmel-1 T cells that were transduced with IRF4 (sample 1, IRF4_Pmel) or GFP control (Sample 3, Ctrl_Pmel), and CD45+ endogenous TILs from either the IRF4 group (Sample 2, IRF4_TILs) or Ctrl group (Sample 4, Ctrl_TILS).
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| |
|
| Overall design |
scRNAseq analysis of TILs from B16-F10 melanoma was performed.
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| |
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| Contributor(s) |
Hui Y, Zou D, Chen W, Dai Y |
| Citation(s) |
37860697 |
| |
| Submission date |
Mar 20, 2023 |
| Last update date |
Oct 31, 2023 |
| Contact name |
Yulin Dai |
| E-mail(s) |
Yulin.Dai@uth.tmc.edu
|
| Organization name |
University of Texas health science center at Houston
|
| Department |
School of Biomedical Informatics
|
| Street address |
7000 fannin, suite 600
|
| City |
Houston |
| State/province |
TX |
| ZIP/Postal code |
77030 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL9185 |
Illumina Genome Analyzer (Mus musculus) |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA946670 |
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