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| Status |
Public on Mar 27, 2023 |
| Title |
Tmem161a is an important regulator for bone formation and bone strength through P38 MAPK pathway |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Bone remoding is an extraordinarily complex process involving a variety of factors, such as genetic, metabolic and environmental impacts. Among them, genetic factor plays a major role, but not all have been identified.
We investigated the role of Transmembrane 161a (Tmem161a) in bone structure and function using wild-type (WT) and Tmem161a depleted (Tmem161aGT/GT) mice.
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| Overall design |
Microarray analysis was used to screen for genes that are related to Tmem161a expression. RNA was isolated from WT and Tmem161a-KO cells (n = 3 each), and cRNA was prepared. cRNA from each sample was hybridized to a pre-equilibrated Clariom S mouse. microarray chip, which was then washed, stained, and scanned in an HP ChipScanner (Affymetrix Inc., Santa Clara, USA).
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| Contributor(s) |
Nagai T, Choijookhuu N |
| Citation missing |
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| Submission date |
Mar 22, 2023 |
| Last update date |
Mar 30, 2023 |
| Contact name |
TAKUYA NAGAI |
| E-mail(s) |
takuya_nagai@med.miyazaki-u.ac.jp
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| Phone |
81-985-85-0986
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| Organization name |
University of MIyazaki
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| Department |
Department of Medicine of Sensory and Motor Organs, Faculty of Medicine,
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| Street address |
Kiyotake Kihara 5200
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| City |
Miyazaki |
| State/province |
Miyazaki |
| ZIP/Postal code |
889-1692 |
| Country |
Japan |
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| Platforms (1) |
| GPL23038 |
[Clariom_S_Mouse] Affymetrix Clariom S Assay, Mouse (Includes Pico Assay) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA947585 |
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