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Series GSE228841 Query DataSets for GSE228841
Status Public on Mar 04, 2024
Title COVID-19 vaccination is associated with attenuation of inflammatory responses during breakthrough disease [small RNA-Seq]
Organism Homo sapiens
Experiment type Non-coding RNA profiling by high throughput sequencing
Summary A subset of individualsenrolledina randomised controlled trial ofChAdOx1 nCoV-19 and received either ChAdOx1 COVID-19 or control MenACWY vaccine whoexperienced COVID-19-associated symptoms were evaluated using multi-omictechnologies. Participants were selected to represent symptomatic individuals with and without COVID-19 as determined by a nucleic acid amplification test (NAAT) for stage 1 and only NAAT+ve for stage 2 of the study.
 
Overall design Blood samples taken on theday of vaccination were compared with samples taken at onset of COVID-19 associated symptoms and 7 days later.Small RNA sequencing technology was utilised.
 
Contributor(s) Chelysheva I, Drury R, O'Connor D, Camara S
Citation(s) 38649734
Submission date Apr 03, 2023
Last update date May 17, 2024
Contact name Irina Chelysheva
E-mail(s) irina.chelysheva@ndm.ox.ac.uk
Organization name University of Oxford
Department NDM
Lab Centre for Human Genetics
Street address Roosevelt Dr
City Oxford
ZIP/Postal code OX3 7BN
Country United Kingdom
 
Platforms (1)
GPL18573 Illumina NextSeq 500 (Homo sapiens)
Samples (180)
GSM7140139 WTCHG_853846_201_CT+7_ChAdOx1_-ve
GSM7140140 WTCHG_853846_202_D0_MenACWY_-ve
GSM7140141 WTCHG_853846_203_CT_MenACWY_-ve
This SubSeries is part of SuperSeries:
GSE228842 COVID-19 vaccination is associated with attenuation of inflammatory responses during breakthrough disease
Relations
BioProject PRJNA951718

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE228841_stage1_smallrnaseq_raw_counts.txt.gz 1.3 Mb (ftp)(http) TXT
GSE228841_stage2_smallrnaseq_raw_counts.txt.gz 4.8 Mb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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