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| Status |
Public on Jul 06, 2023 |
| Title |
Regulation of oxidative stress in endothelial cells exposed to high glucose by selected microRNA |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Hyperglycemia is the hallmark of diabetes mellitus that results in oxidative stress, endothelial dysfunction and vascular complications of diabetes. MicroRNAs (miRNAs) play a role in the development of endothelial dysfunction in diabetes, with potential application for the future therapy of diabetic vascular complications. However, there is a limited number of studies that characterize the miRNA profile of endothelial cells exposed to hyperglycemic condition. This study aimed to identify the miRNA profile of human umbilical vein endothelial cells (HUVEC) exposed to hyperglycemic state using RNA sequencing analysis.
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for HUVEC
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| |
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| Contributor(s) |
Othman NS, Ugusman A, Hamid AA, Aminuddin A |
| Citation(s) |
37374078 |
| BioProject |
PRJNA951459 |
| |
| Submission date |
Apr 07, 2023 |
| Last update date |
Jul 06, 2023 |
| Contact name |
Nur Syakirah Binti Othman |
| E-mail(s) |
p118667@siswa.ukm.edu.my
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| Organization name |
National University of Malaysia
|
| Department |
Physiology
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| Street address |
Yaacob Latiff Street
|
| City |
Cheras |
| State/province |
Kuala Lumpur |
| ZIP/Postal code |
56000 |
| Country |
Malaysia |
| |
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| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
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| Samples (6)
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