|
Status |
Public on Apr 07, 2011 |
Title |
Genome-Wide Analysis of Somatic Copy Number Alterations and Gene Expression in Metastatic Melanoma: RNA-Seq |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by high throughput sequencing
|
Summary |
All cancers are diseases of the genome. A combination of somatic point mutations, focal amplifications and deletions, and chromosome level aberrations conspire to disrupt gene expression and the interplay between signaling pathways that control normal growth and tissue homeostasis. Here we investigate transcript levels in 7 melanomas and a pool of melanocytes.
|
|
|
Overall design |
The transcriptome from 7 cutaneous melanomas and a pool of 2 normal melanocyte cultures was sequenced using the 454 technology
|
|
|
Contributor(s) |
Stevenson BJ, Valsesia A |
Citation(s) |
21494657 |
|
Submission date |
Jul 14, 2010 |
Last update date |
May 15, 2019 |
Contact name |
Armand Valsesia |
Organization name |
Ludwig Institute for Cancer Research
|
Street address |
Bâtiment Génopode
|
City |
Lausanne |
ZIP/Postal code |
1015 |
Country |
Switzerland |
|
|
Platforms (1) |
|
Samples (8)
|
GSM566259 |
LAU-Me280.R.LN melanoma cells patient LAU165 (454) |
GSM566260 |
Normal melanocytes pool of 2 samples (454) |
GSM566261 |
LAU-T618A melanoma cells patient LAU618 (454) |
GSM566262 |
LAU-T149D melanoma cells patient LAU149D (454) |
GSM566263 |
LAU-Me235 melanoma cells patient LAU63 (454) |
GSM566264 |
LAU-Me246.M1melanoma cells patient LAU108 (454) |
GSM566265 |
LAU-Me275 melanoma cells patient LAU50 (454) |
GSM566266 |
LAU-T50B melanoma cells patient LAU50 (454) |
|
This SubSeries is part of SuperSeries: |
GSE23056 |
Genome-Wide Analysis of Somatic Copy Number Alterations and Gene Expression in Metastatic Melanoma |
|
Relations |
SRA |
SRP003173 |
BioProject |
PRJNA133097 |