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| Status |
Public on May 12, 2023 |
| Title |
Effects of hunger on neuronal histone modifications slow aging in Drosophila |
| Organism |
Drosophila melanogaster |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To determine how dietary BCAAs modulate transcriptional networks in the brain, we designed three diets of varying BCAA concentrations (low BCAA, reference diet, and high BCAA).
We performed transcriptional profiling of brains using RNA-seq after flies had been on one of three BCAA diets for one week.
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for brains of flies on reference diets, low BCAA, or high BCAA diets.
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| Web link |
https://www.science.org/doi/10.1126/science.ade1662
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| |
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| Contributor(s) |
Pletcher SD, Lyu Y, Weaver KJ |
| Citation(s) |
37167393 |
| |
| Submission date |
Apr 10, 2023 |
| Last update date |
May 14, 2023 |
| Contact name |
Scott D Pletcher |
| E-mail(s) |
spletch@umich.edu
|
| Organization name |
University of Michigan
|
| Street address |
109 Zina Pitcher Pl
|
| City |
Ann Arbor |
| State/province |
MI |
| ZIP/Postal code |
48109 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL19132 |
Illumina NextSeq 500 (Drosophila melanogaster) |
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| Samples (24)
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| Relations |
| BioProject |
PRJNA954029 |
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