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| Status |
Public on Dec 31, 2023 |
| Title |
Investigating the role of telomere length in 3D spatiotemporal gene regulation in cardiomyocytes [CUT&Tag] |
| Organism |
Homo sapiens |
| Experiment type |
Genome variation profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
Telomeres, TTAGGGn DNA repeat sequences located at the ends of eukaryotic chromosomes, play a pivotal role in ageing and are targets of DNA damage and DNA damage response. Although short telomeres have been implicated in heart failure, little is known about the role of telomeres in cardiomyocytes.To fill this gap in knowledge, we studied myocardial ageing in the form of telomere lengths under isogenic background.
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| |
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| Overall design |
CUT&Tag for FOXC1 in CONTROL and FOXC1 OE hiPSCs-derived cardiomyocytes.
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| |
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| Contributor(s) |
Chang AC, Bian Q, Li B, zuo W |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Apr 24, 2023 |
| Last update date |
Jan 01, 2024 |
| Contact name |
Bin Li |
| E-mail(s) |
leo1989jt@gmail.com
|
| Organization name |
Shanghai jiaotong University
|
| Street address |
Jinzun Road
|
| City |
Shanghai |
| ZIP/Postal code |
200120 |
| Country |
China |
| |
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| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (10)
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| This SubSeries is part of SuperSeries: |
| GSE217703 |
Investigating the role of telomere length in 3D spatiotemporal gene regulation in cardiomyocytes |
|
| Relations |
| BioProject |
PRJNA961155 |
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