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Series GSE230684 Query DataSets for GSE230684
Status Public on Jul 05, 2023
Title Epigenetic landscape of Human Brains by Single Nucleus Methylation Sequencing - pool3_h1930001_CBV
Organism Homo sapiens
Experiment type Methylation profiling by high throughput sequencing
Summary Illustrating the cellular architecture of the human brain is critical to understanding its diverse functions and complex animal behaviors. Single nucleus methylation sequencing was applied to regions of human brains. we identified distinct cell clusters and formed them in a hierarchical taxonomy. These clusters include known primary brain cell types and possible sub-types. We use these data to identify the epigenomic characteristics and to define specific regulatory elements for each cell cluster.
 
Overall design Apply snmC-seq3 to brain regions to identify epigenomic landcape of the adult human brains
 
Contributor(s) Tian W, Bartlett A, Liu H, Altshul J, Gomez Castanon R, Nery JR, Chen H, Ecker JR
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Apr 26, 2023
Last update date Jul 06, 2023
Contact name Joseph R Ecker
E-mail(s) ecker@salk.edu
Phone 8584534100
Organization name HHMI-Salk-Institute
Department Genomic Analysis Laboratory
Lab Ecker lab
Street address 10010 North Torrey Pines Road
City La Jolla
State/province CA
ZIP/Postal code 92037
Country USA
 
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (1313)
GSM7231239 HBA_191216_H1930001_CB60_CBV_2_P1-1-J18-A1
GSM7231240 HBA_191216_H1930001_CB60_CBV_2_P1-1-J18-A13
GSM7231241 HBA_191216_H1930001_CB60_CBV_2_P1-1-J18-A14
Relations
BioProject PRJNA962131
SRA SRP434722

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE230684_RAW.tar 99.1 Gb (http)(custom) TAR (of TSV)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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