|
| Status |
Public on Apr 26, 2024 |
| Title |
The initial age-associated decline in early T-cell progenitors reflects fewer pre-thymic progenitors and altered signals in the bone marrow and thymus microenvironments |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To identify candidatemechanisms underlying the early decline in CLPs and MPPs by 3MO.
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| |
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| Overall design |
We carried out bulk RNA-seq on 1MO v 3MO CLPs and MPPs (N=3 independent experimental repeats) using 150bp paired-end sequencing with a target of 20 million reads per sample.
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| |
|
| Contributor(s) |
Ehrlich LI, Richie ER, Srinivasan J, Vasudev A |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Apr 27, 2023 |
| Last update date |
Apr 26, 2024 |
| Contact name |
Lauren I.R. Ehrlich |
| Organization name |
University of Texas at Austin
|
| Lab |
Ehrlich lab
|
| Street address |
Neural and Molecular Sciences building
|
| City |
Austin |
| State/province |
TX |
| ZIP/Postal code |
78712 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (12)
|
|
| Relations |
| BioProject |
PRJNA962454 |
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