|
| Status |
Public on Oct 16, 2024 |
| Title |
Interplay between nutrient stress and lysosomal signaling imprints immune memory in tissues [scRNAseq] |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Uncovered organelle signaling and metabolic processes shaping CD8+ tissue-resident memory (TRM) development
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| |
|
| Overall design |
We used scRNAseq to compare gene transcriptome profiles of sgNTC or sgFlcn-transduced OT-1 cells purified from the siIEL on days 4.5 and 7.5 post-LM-OVA infection
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| |
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| Contributor(s) |
Shi H, Raynor JL, Chi H |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
May 02, 2023 |
| Last update date |
Oct 17, 2024 |
| Contact name |
Hongbo Chi |
| E-mail(s) |
hongbo.chi@stjude.org
|
| Organization name |
St Jude Children's Research Hospital
|
| Department |
Immunology
|
| Street address |
262 Danny Thomas Place
|
| City |
Memphis |
| State/province |
TN |
| ZIP/Postal code |
38105 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
|
| Samples (8)
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| This SubSeries is part of SuperSeries: |
| GSE231502 |
CRISPR screens unveil nutrient-dependent lysosomal and mitochondrial nodes impacting intestinal tissue-resident memory CD8+ T cell formation |
|
| Relations |
| BioProject |
PRJNA966160 |
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