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Status |
Public on Oct 16, 2024 |
Title |
Interplay between nutrient stress and lysosomal signaling imprints immune memory in tissues [scRNAseq] |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
Uncovered organelle signaling and metabolic processes shaping CD8+ tissue-resident memory (TRM) development
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Overall design |
We used scRNAseq to compare gene transcriptome profiles of sgNTC or sgFlcn-transduced OT-1 cells purified from the siIEL on days 4.5 and 7.5 post-LM-OVA infection
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Contributor(s) |
Shi H, Raynor JL, Chi H |
Citation missing |
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Submission date |
May 02, 2023 |
Last update date |
Oct 17, 2024 |
Contact name |
Hongbo Chi |
E-mail(s) |
hongbo.chi@stjude.org
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Organization name |
St Jude Children's Research Hospital
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Department |
Immunology
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Street address |
262 Danny Thomas Place
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City |
Memphis |
State/province |
TN |
ZIP/Postal code |
38105 |
Country |
USA |
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Platforms (1) |
GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
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Samples (8)
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This SubSeries is part of SuperSeries: |
GSE231502 |
CRISPR screens unveil nutrient-dependent lysosomal and mitochondrial nodes impacting intestinal tissue-resident memory CD8+ T cell formation |
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Relations |
BioProject |
PRJNA966160 |