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| Status |
Public on May 18, 2024 |
| Title |
Ubiquitination of hepatic APOC3 by GM47544 prevents hypertriglyceridemia and ameliorates atherosclerosis |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
To investigate the function of lnc GM47544 in the regulation of triglyceride, we established AML-12 cell lines in which lnc GM47544 has been stably overexpressed by lentivirus.
We then performed gene expression profiling analysis using data obtained from RNA-seq of AML-12-pLKO.1 (control) and AML-12-GM47544 (O/E).
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for AML-12-pLKO.1 (control) and AML-12-GM47544 (O/E).
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| Contributor(s) |
Xiao Q, Ding H |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
May 19, 2023 |
| Last update date |
May 18, 2024 |
| Contact name |
Qianqian Xiao |
| Organization name |
Tongji Hospital
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| Department |
Departments of Internal Medicine
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| Lab |
Division of Cardiology
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| Street address |
1095# Jiefang Ave., Wuhan 430030 People’s Rep. of China
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| City |
Wuhan |
| ZIP/Postal code |
430030 |
| Country |
China |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (8)
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| GSM7385131 |
AML-12 cells, control, pLKO.1-4 |
| GSM7385132 |
AML-12 cells, overexpression, GM47544-1 |
| GSM7385133 |
AML-12 cells, overexpression, GM47544-2 |
| GSM7385134 |
AML-12 cells, overexpression, GM47544-3 |
| GSM7385135 |
AML-12 cells, overexpression, GM47544-4 |
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| Relations |
| BioProject |
PRJNA974253 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE232866_All.HTSeq.counts.txt.gz |
283.3 Kb |
(ftp)(http) |
TXT |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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