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| Status |
Public on Jun 15, 2024 |
| Title |
miRNA expression profiles of exosomes from polarized bone marrow derived macrophages |
| Organism |
Mus musculus |
| Experiment type |
Non-coding RNA profiling by high throughput sequencing
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| Summary |
Unprogrammed macrophage polarization, is associated with diabetic wound ulcers. Nevertheless, development of corresponding drugs is still a challenge. Here, exosomes are isolated from naive bone marrow-derived macrophages (BMDMs) (M0-Exos), inflammatory BMDMs (M1-Exos), and anti-inflammatory BMDMs (M2-Exos), with the aim of pinpointing the exosomes functionality and identify global miRNAs expression profiles.
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| Overall design |
Expression profile analysis of exosomal microRNA data from M1(pro-inflammatory macrophages), M2 (anti-inflammatory macrophages) and M0 (unpolarized macrophages).
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| Contributor(s) |
Lin L, Lou R |
| Citation missing |
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| Submission date |
Jun 14, 2023 |
| Last update date |
Jun 15, 2024 |
| Contact name |
Ruohan Lou |
| Organization name |
University of Macau
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| Street address |
Avenida da Universidade
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| City |
Taipa, Macau |
| ZIP/Postal code |
999078 |
| Country |
Macau |
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| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
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| Samples (9)
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| GSM7486577 |
Anti-inflammatory BMDMs exosomes, biol rep 1 |
| GSM7486578 |
Anti-inflammatory BMDMs exosomes, biol rep 2 |
| GSM7486579 |
Anti-inflammatory BMDMs exosomes, biol rep 3 |
| GSM7486580 |
Pro-inflammatory BMDMs exosomes, biol rep 1 |
| GSM7486581 |
Pro-inflammatory BMDMs exosomes, biol rep 2 |
| GSM7486582 |
Pro-inflammatory BMDMs exosomes, biol rep 3 |
| GSM7486583 |
Unpolarized BMDMs exosomes, biol rep 1 |
| GSM7486584 |
Unpolarized BMDMs exosomes, biol rep 2 |
| GSM7486585 |
Unpolarized BMDMs exosomes, biol rep 3 |
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| Relations |
| BioProject |
PRJNA983796 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE234953_RAW.tar |
40.0 Kb |
(http)(custom) |
TAR (of TXT) |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
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