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Status |
Public on Jul 05, 2023 |
Title |
Depletion of pyruvate kinase (PK) activity causes glycolytic intermediate imbalances and reveals a PK-TXNIP regulatory axis. |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by high throughput sequencing Genome binding/occupancy profiling by high throughput sequencing
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Summary |
This SuperSeries is composed of the SubSeries listed below.
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Overall design |
Refer to individual Series
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Citation(s) |
37290673 |
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Submission date |
Jun 20, 2023 |
Last update date |
Sep 12, 2023 |
Contact name |
Robert Schneider |
Organization name |
Helmholtz Zentrum München
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Department |
Institute of Functional Epigenetics
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Street address |
Ingolstädter Landstraße 1
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City |
Oberschleißheim |
ZIP/Postal code |
85764 |
Country |
Germany |
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Platforms (2) |
GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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Samples (42)
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GSM7501578 |
HEK293, PKM KD, Replicate 1.3 |
GSM7501579 |
HEK293, PKM KD, Replicate 1.2 |
GSM7501580 |
HEK293, PKM KD, Replicate 1.1 |
GSM7501581 |
HEK293, PKM KD, Replicate 2.1 |
GSM7501582 |
HEK293, PKM KD, Replicate 2.2 |
GSM7501583 |
HEK293, PKM KD, Replicate 2.3 |
GSM7501584 |
HEK293, WT, Replicate 2.1 |
GSM7501585 |
HEK293, WT, Replicate 2.2 |
GSM7501586 |
HEK293, WT, Replicate 2.3 |
GSM7501587 |
MCF-7, WT, Replicate 1, L001 |
GSM7501588 |
MCF-7, PKM KD, Replicate 1, L001 |
GSM7501589 |
MCF-7, WT, Replicate 2, L001 |
GSM7501590 |
MCF-7, PKM KD, Replicate 2, L001 |
GSM7501591 |
MCF-7, WT, Replicate 1, L002 |
GSM7501592 |
MCF-7, PKM KD, Replicate 1, L002 |
GSM7501593 |
MCF-7, WT, Replicate 2, L002 |
GSM7501594 |
MCF-7, PKM KD, Replicate 2, L002 |
GSM7501595 |
HEK293, PKM KD, H3K4me3 ChIP, Replicate 1 |
GSM7501596 |
HEK293, PKM KD, H3K4me3 ChIP, Replicate 2 |
GSM7501597 |
HEK293, WT, H3K4me3 ChIP, Replicate 1 |
GSM7501598 |
HEK293, WT, H3K4me3 ChIP, Replicate 2 |
GSM7501599 |
HEK293, PKM KD, H3K9ac ChIP, Replicate 1 |
GSM7501600 |
HEK293, PKM KD, H3K9ac ChIP, Replicate 2 |
GSM7501601 |
HEK293, WT, H3K9ac ChIP, Replicate 1 |
GSM7501602 |
HEK293, WT, H3K9ac ChIP, Replicate 2 |
GSM7501603 |
HEK293, PKM KD, Input, Batch 1, Replicate 1 |
GSM7501604 |
HEK293, PKM KD, Input, Batch 1, Replicate 2 |
GSM7501605 |
HEK293, PKM KD, Input, Batch 2, Replicate 1&2 |
GSM7501606 |
HEK293, WT, Input, Batch 1, Replicate 1 |
GSM7501607 |
HEK293, WT, Input, Batch 1, Replicate 2 |
GSM7501608 |
HEK293, WT, Input, Batch 2, Replicate 1&2 |
GSM7501609 |
HEK293, PKM KD, MLX ChIP, Replicate 1 |
GSM7501610 |
HEK293, PKM KD, MLX ChIP, Replicate 2 |
GSM7501611 |
HEK293, WT, MLX ChIP, Replicate 1 |
GSM7501612 |
HEK293, WT, MLX ChIP, Replicate 2 |
GSM7501613 |
HEK293, PKM KD, MondoA ChIP, Replicate 1 |
GSM7501614 |
HEK293, PKM KD, MondoA ChIP, Replicate 2 |
GSM7501615 |
HEK293, WT, MondoA ChIP, Replicate 1 |
GSM7501616 |
HEK293, WT, MondoA ChIP, Replicate 2 |
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This SuperSeries is composed of the following SubSeries: |
GSE235387 |
Depletion of pyruvate kinase (PK) activity causes glycolytic intermediate imbalances and reveals a PK-TXNIP regulatory axis [RNA-seq] |
GSE235388 |
Depletion of pyruvate kinase (PK) activity causes glycolytic intermediate imbalances and reveals a PK-TXNIP regulatory axis [ChIP-seq] |
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Relations |
BioProject |
PRJNA985771 |
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