|
| Status |
Public on Nov 01, 2023 |
| Title |
Hypermethylation suppresses microRNA-219a-2 to activate the ALDH1L2/GSH/PAI-1 pathway for fibronectin degradation in renal fibrosis |
| Organisms |
Homo sapiens; Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
Other
Methylation profiling by high throughput sequencing
|
| Summary |
This SuperSeries is composed of the SubSeries listed below.
|
| |
|
| Overall design |
Refer to individual Series
|
| |
|
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Jun 28, 2023 |
| Last update date |
Nov 01, 2023 |
| Contact name |
Qingqing Wei |
| E-mail(s) |
QWEI@AUGUSTA.EDU
|
| Phone |
7067213551
|
| Organization name |
Augusta University
|
| Department |
Cellular Biology & Anatomy
|
| Lab |
CB1124
|
| Street address |
1460 Laney Walker Blvd.
|
| City |
AUGUSTA |
| State/province |
Georgia |
| ZIP/Postal code |
30912 |
| Country |
USA |
| |
|
| Platforms (2) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (14)
|
| GSM7510561 |
HEK293 cells with mir-219 mimics, sample on 8/22 |
| GSM7510562 |
HEK293 cells with mir-219 mimics, sample on 9/5 |
| GSM7510563 |
HEK293 cells with mir-219 mimics, sample on 9/18 |
| GSM7510564 |
HEK293 cells with negative control mimics, sample on 8/22 |
| GSM7510565 |
HEK293 cells with negative control mimics, sample on 9/5 |
| GSM7510566 |
HEK293 cells with negative control mimics, sample on 9/18 |
| GSM7516854 |
mouse kidney, UUO7D, sample 1 |
| GSM7516855 |
mouse kidney, UUO7D, sample 2 |
| GSM7516856 |
mouse kidney, sham sample 1 for UUO7D |
| GSM7516857 |
mouse kidney, bilateral kidney ischemia 25 minutes and 1 month reperfusion |
| GSM7516858 |
mouse kidney, bilateral kidney ischemia 25 minutes and 1 week reperfusion |
| GSM7516859 |
mouse kidney, sham for kidney ischemia/reperfusion |
| GSM7516860 |
mouse kidney, UUO7D, 5AZA, sample 1 |
| GSM7516861 |
mouse kidney, UUO7D, 5AZA, sample 2 |
|
| This SuperSeries is composed of the following SubSeries: |
| GSE235842 |
Hypermethylation suppresses microRNA-219a-2 to activate the ALDH1L2/GSH/PAI-1 pathway for fibronectin degradation in renal fibrosis [RIP-Seq] |
| GSE236018 |
Hypermethylation suppresses microRNA-219a-2 to activate the ALDH1L2/GSH/PAI-1 pathway for fibronectin degradation in renal fibrosis [RRBS] |
|
| Relations |
| BioProject |
PRJNA988437 |
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