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| Status |
Public on Jul 08, 2023 |
| Title |
the Arraystar Human m6A-mRNA&lncRNA Epitranscriptomic microarray analysis in the neutrophils of ischemic stroke patients and healthy controls |
| Organism |
Homo sapiens |
| Experiment type |
Other
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| Summary |
The high incidence, mortality, and disability rate of ischemic stroke impose huge economic burdens on patients and social health care systems.N6-methyladenosine (m6A) is one of the most extensive RNA methylation modifications in eukaryotes and participates in the pathogenesis of numerous diseases including ischemic stroke. Peripheral blood neutrophils are forerunners after ischemic brain injury and exert crucial functions.However, the underlying mechanisms of neutrophils in ischemic stroke need to be further clarified. This study aims to explore the transcriptional profiles of m6A modification in neutrophils of patients with ischemic stroke.
The Arraystar Human m6A-mRNA&lncRNA Epitranscriptomic microarray analysis was performed on the peripheral blood neutrophils of 3 patients with ischemic stroke and 3 healthy controls, providing the clinical significance of m6A modification on ischemic stroke.
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| Overall design |
All participants were divided into 2 groups: acute ischemic stroke patients (Trial group) and healthy controls (Control group), each containing 3 participants.
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| Contributor(s) |
Fan J, Luo Y |
| Citation missing |
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| Submission date |
Jul 03, 2023 |
| Last update date |
Jul 08, 2023 |
| Contact name |
JUNFEN FAN |
| E-mail(s) |
fanjunfen@xwhosp.org
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| Organization name |
Xuanwu hospital of Capital Medical University
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| Street address |
45 Changchun St, Beijing 100053, China
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| City |
Beijing |
| ZIP/Postal code |
100053 |
| Country |
China |
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| Platforms (1) |
| GPL25759 |
Agilent-085753 Arraystar Human Epitranscriptomic microarray |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA990727 |
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