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Series GSE23748 Query DataSets for GSE23748
Status Public on Aug 27, 2011
Title Tofu decreases serum lipid levels and modulates hepatic gene expression involved in lipid metabolism in rats
Organism Rattus norvegicus
Experiment type Expression profiling by array
Summary The effects of freeze-dried tofu, a traditional Japanese soy food, were compared with those of major active soy components, protein and isoflavone, by observing physiological differences and global transcriptomes in the liver of male rats.
The GeneChip data was normalized and summarized by using SuperNORM data service (Skylight Biotech Inc.). Significance of expressional change among groups was tested by 2-way ANOVA on the normalized CEL data, which was deposited in a tab-separated ASCII text format. Principal components were identified on the summarized gene data.
Overall design Rats were randomly divided into 6 groups of 5 samples and assigned experimental diets for 14 days. The experimental diets were as follows: casein diet (C); C containing isoflavone (CI) soy protein diet (S); S containing isoflavone (SI); a diet containing 100 g/kg each of protein derived from casein and freeze-dried tofu (T10); a diet containing 200 g/kg of protein derived from freeze-dried tofu (T20). CI and SI were supplemented with a mixture of isoflavones to match the isoflavone level of T20.
Contributor(s) Takahashi Y, Konishi T
Citation(s) 21721588
Submission date Aug 23, 2010
Last update date Jul 31, 2017
Contact name Tomokazu Konishi
Phone +81-18-872-1603
Organization name Akita Prefectural University
Department Bioresource Sciences
Lab Molecular Genetics
Street address Shimoshinjyo Nishi
City Akita
State/province Akita
ZIP/Postal code 010-0195
Country Japan
Platforms (1)
GPL1355 [Rat230_2] Affymetrix Rat Genome 230 2.0 Array
Samples (30)
GSM586045 casein diet, biological rep1
GSM586046 casein diet, biological rep2
GSM586047 casein diet, biological rep3
BioProject PRJNA130753

ANOVA header descriptions
ID_REF probe set id
n the number of cells to be used in the ANOVA analysis
express P-values for afmong-group differences
cell:express P-values for the interactions between cell sensitivity and groups

Data table
ID_REF n express cell:express
1367452_at 11 0.000237619 0.999348542
1367453_at 11 7.03E-08 0.976817475
1367454_at 11 0.008464597 0.19515684
1367455_at 11 1.39E-27 0.003487143
1367456_at 11 0.00036681 0.999998748
1367457_at 11 1.15E-14 0.995921146
1367458_at 11 0.004450241 0.80044332
1367459_at 11 1.29E-14 0.898714392
1367460_at 11 9.24E-09 1
1367461_at 11 3.95E-10 0.999999931
1367462_at 11 0.004222479 0.999830946
1367463_at 11 1.26E-13 0.999981552
1367464_at 11 5.25E-35 0.984976383
1367465_at 11 5.33E-34 0.985051737
1367466_at 11 6.30E-33 0.894557475
1367467_at 11 1.52E-16 0.583540708
1367468_at 11 0.000173332 0.999999994
1367469_at 11 0.002388446 0.999999955
1367470_at 11 6.10E-12 0.99977536
1367471_at 11 1.65E-35 0.995589344

Total number of rows: 31099

Table truncated, full table size 1094 Kbytes.

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE23748_ANOVA_README.txt 1.1 Kb (ftp)(http) TXT
GSE23748_RAW.tar 75.3 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table
Processed data are available on Series record

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