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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Jan 03, 2024 |
| Title |
Hemorrhage-induced NRF2 signaling in tumor-associated macrophages drives cancer growth, invasion, and immunotherapy resistance |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
This SuperSeries is composed of the SubSeries listed below.
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| Overall design |
Refer to individual Series
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| Citation(s) |
38060331 |
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| Submission date |
Jul 18, 2023 |
| Last update date |
Feb 15, 2024 |
| Contact name |
Florence Vallelian |
| E-mail(s) |
florence.vallelian@usz.ch
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| Organization name |
University Hospital Zürich
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| Street address |
Rämistrasse 100
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| City |
Zurich |
| ZIP/Postal code |
8091 |
| Country |
Switzerland |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (29)
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| This SuperSeries is composed of the following SubSeries:
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| GSE236439 |
Red blood cell heme drives the generation of TAM-like macrophages with an immunocompromized phenotype |
| GSE236576 |
Mixed cell-type spheroids endorse the generation and maintenance of heme-TAMs in an experimental tumor microenvironment |
| GSE236995 |
Heme-TAMs prevent cancer cell apoptosis and drive growth, invasiveness, and metastasis |
| GSE236996 |
Heme-TAMs are resistant to tumoricidal transformation by INFγ |
| GSE236997 |
Heme-signaling progresses via NRF2 to educate heme-TAM transformation, tumor cell growth, and invasiveness |
| GSE237119 |
Red blood cells-heme-exposure and tumor-associated macrophage identity |
| GSE237238 |
Heme exposure induces the phenotype of Hmox1high, Marcohigh, and MHC class IIlow macrophages |
| GSE237257 |
Mixed cell-type spheroids endorse the generation and maintenance of heme-TAMs in an experimental tumor microenvironment [joint analysis] |
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| Relations |
| BioProject |
PRJNA996034 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE237612_RAW.tar |
1.7 Gb |
(http)(custom) |
TAR (of CSV, H5, H5AD, JPG, JSON, PNG, TXT) |
SRA Run Selector |
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