 |
 |
GEO help: Mouse over screen elements for information. |
|
| Status |
Public on May 30, 2024 |
| Title |
Deletion of the mRNA endonuclease Regnase-1 promotes NK cell anti-tumor activity via OCT2- dependent transcription of Ifng |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
Expression profiling by high throughput sequencing
Other
|
| Summary |
This SuperSeries is composed of the SubSeries listed below.
|
| |
|
| Overall design |
Refer to individual Series
|
| |
|
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Jul 18, 2023 |
| Last update date |
May 30, 2024 |
| Contact name |
Xin Sun |
| E-mail(s) |
sunxin@ifrec.osaka-u.ac.jp
|
| Organization name |
IFReC, Osaka University
|
| Street address |
3-1 Yamadaoka, Suita
|
| City |
Osaka |
| ZIP/Postal code |
5650871 |
| Country |
Japan |
| |
|
| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (58)
|
| GSM7635036 |
WT_Sti, rep 1, ATACseq |
| GSM7635037 |
WT_Sti, rep 2, ATACseq |
| GSM7635038 |
WT_Sti, rep 3, ATACseq |
| GSM7635039 |
KO_Ctl, rep 1, ATACseq |
| GSM7635040 |
KO_Ctl, rep 2, ATACseq |
| GSM7635041 |
KO_Ctl, rep 3, ATACseq |
| GSM7635042 |
KO_Sti, rep 1, ATACseq |
| GSM7635043 |
KO_Sti, rep 2, ATACseq |
| GSM7635044 |
KO_Sti, rep 3, ATACseq |
| GSM7635045 |
WT,GEX, L1 |
| GSM7635046 |
WT,GEX, L2 |
| GSM7635047 |
WT,GEX, L3 |
| GSM7635048 |
WT,GEX, L4 |
| GSM7635049 |
WT, ADT,L1 |
| GSM7635050 |
WT, ADT,L2 |
| GSM7635051 |
WT, ADT,L3 |
| GSM7635052 |
WT, ADT,L4 |
| GSM7635053 |
KO, GEX, L1 |
| GSM7635054 |
KO, GEX, L2 |
| GSM7635055 |
KO, GEX, L3 |
| GSM7635056 |
KO, GEX, L4 |
| GSM7635057 |
KO, ADT, L1 |
| GSM7635058 |
KO, ADT, L2 |
| GSM7635059 |
KO, ADT, L3 |
| GSM7635060 |
KO, ADT, L4 |
| GSM7635061 |
WT_Input, rep 1, ChIPseq |
| GSM7635062 |
WT_Input, rep 2, ChIPseq |
| GSM7635063 |
WT_ChIP, rep 1, ChIPseq |
| GSM7635064 |
WT_ChIP, rep 2, ChIPseq |
| GSM7635065 |
KO_Input, rep 1, ChIPseq |
| GSM7635066 |
KO_Input, rep 2, ChIPseq |
| GSM7635067 |
KO_ChIP, rep 1, ChIPseq |
| GSM7635068 |
KO_ChIP, rep 2, ChIPseq |
| GSM7635069 |
WT_Input, rep 3, ChIPseq |
| GSM7635070 |
WT_ChIP, rep 3, ChIPseq |
| GSM7635071 |
KO_Input, rep 3, ChIPseq |
| GSM7635072 |
KO_ChIP, rep 3, ChIPseq |
| GSM7635073 |
WT_Ctl, rep 1, RNAseq |
| GSM7635074 |
WT_Ctl, rep 2, RNAseq |
| GSM7635075 |
WT_Ctl, rep 3, RNAseq |
| GSM7635076 |
WT_Sti, rep 1, RNAseq |
| GSM7635077 |
WT_Sti, rep 2, RNAseq |
| GSM7635078 |
WT_Sti, rep 3, RNAseq |
| GSM7635079 |
KO_Ctl, rep 1, RNAseq |
| GSM7635080 |
KO_Ctl, rep 2, RNAseq |
| GSM7635081 |
KO_Ctl, rep 3, RNAseq |
| GSM7635082 |
KO_Sti, rep 1, RNAseq |
| GSM7635083 |
KO_Sti, rep 2, RNAseq |
| GSM7635084 |
KO_Sti, rep 3, RNAseq |
| GSM7635085 |
WT_NK |
| GSM7635086 |
KO_NK |
| GSM7635087 |
WT_tumor |
| GSM7635088 |
KO_tumor |
| GSM7846850 |
WT |
| GSM7846851 |
KO |
|
| This SuperSeries is composed of the following SubSeries:
|
| GSE237637 |
The transcriptional landscape associated with the deletion of Regnase-1 [ATAC-Seq] |
| GSE237639 |
Transcriptomic profile at single cell level of splenic NK cells from Reg-1fl/fl and Reg-1ΔNK mice [CITE-Seq] |
| GSE237640 |
Identification of the genome-wide binding sites of OCT2 in Reg-1fl/fl- and Reg-1ΔNK-NK cells. [ChIP-Seq] |
| GSE237641 |
The transcriptional landscape associated with the deletion of Regnase-1 [RNA-Seq] |
| GSE237642 |
Transcriptomic profile at single cell level of TIL-NK cells and tumor cells from tumor-bearing Reg-1fl/fl and Reg-1ΔNK mice |
| GSE245678 |
Transcriptomic profile at single cell level of OCT2fl/fl and Ncr(+)/OCT2fl/fl mice [scRNA-seq] |
|
| Relations |
| BioProject |
PRJNA996077 |
|
|
|
|
 |
Less...
More...