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Status |
Public on Feb 27, 2024 |
Title |
Identification of Foxp1 regulating target genes in renal cells using ChIP-seq sequencing |
Organism |
Mus musculus |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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Summary |
To investigate the specific role of Foxp1 in kidney tubular system, we specifically deleted Foxp1 expression in kidney distal nephrons and collecting ducts. We examined the effects of Foxp1 on IC differentiation and urine acidification. Chip-seq was used to identify Foxp1 target genes.
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Overall design |
To identify potential direct target genes of Foxp1 in kidney distal tubules, we performed ChIP-seq analysis with kidney tissues from Foxp1kspKO and littermate control mice.
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Contributor(s) |
Wu S, Lu D, Feng Y, Song R |
Citation(s) |
38332484 |
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Submission date |
Jul 26, 2023 |
Last update date |
Mar 06, 2024 |
Contact name |
RENHUA SONG |
E-mail(s) |
Renhua.song1989@gmail.com
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Phone |
61452667663
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Organization name |
Centenary Institute
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Lab |
Epigenetics and RNA Biology Program
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Street address |
Charles Perkins Centre - D17, Level 4 West. The University of Sydney Johns Hopkins Drive
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City |
Camperdown |
State/province |
NSW |
ZIP/Postal code |
2050 |
Country |
Australia |
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Platforms (1) |
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Samples (4)
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This SubSeries is part of SuperSeries: |
GSE238268 |
Foxp1 is required for renal intercalated cell differentiation and acid-base regulation |
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Relations |
BioProject |
PRJNA998704 |