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| Status |
Public on Feb 20, 2024 |
| Title |
Bacterial single cell RNA-seq unveils cyclic-di-GMP as an antitoxin critical for antibiotic tolerance in biofilm. |
| Organisms |
Staphylococcus aureus; Pseudomonas aeruginosa PAO1; Escherichia coli str. K-12 substr. MG1655 |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
Expression profiling by high throughput sequencing
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| Summary |
This SuperSeries is composed of the SubSeries listed below.
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| Overall design |
Refer to individual Series
** The submitter states that the study's data have undergone significant changes and are no longer accurately reflected in SuperSeries GSE239505 [Feb 20, 2024]. The correct data are in SuperSeries GSE260458. **
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| Web link |
https://assets.researchsquare.com/files/rs-3329601/v1/579c700c-8679-4c2a-9ee4-dff08841c51a.pdf?c=1700559269
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| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Jul 28, 2023 |
| Last update date |
Mar 01, 2024 |
| Contact name |
Xiaodan Yan |
| E-mail(s) |
2019206500042@whu.edu.cn
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| Phone |
13283874287
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| Organization name |
Wuhan University
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| Department |
Medical Research Institute
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| Street address |
Donghu Road, No. 115, Wuchang District,
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| City |
Wuhan |
| State/province |
Hubei Province |
| ZIP/Postal code |
430071 |
| Country |
China |
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| Platforms (3) |
| GPL26592 |
Illumina NovaSeq 6000 (Escherichia coli str. K-12 substr. MG1655) |
| GPL27158 |
Illumina NovaSeq 6000 (Staphylococcus aureus) |
| GPL28916 |
Illumina NovaSeq 6000 (Pseudomonas aeruginosa PAO1) |
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| Samples (21)
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| GSM7666356 |
Chip, HipH-flag-CDG, IP, replicate 2 |
| GSM7666357 |
Chip, IgG, replicate 1 |
| GSM7666358 |
Chip, IgG, replicate 2 |
| GSM7666359 |
3h, RNA-seq |
| GSM7666360 |
EC-24h-static-ΔΔ, replicate 1, scRNA-seq |
| GSM7666361 |
EC-24h-static-ΔΔ, replicate 2, scRNA-seq |
| GSM7666362 |
EC-3h-ΔΔ, replicate 1, scRNA-seq |
| GSM7666363 |
EC-3h-ΔΔ, replicate 2, scRNA-seq |
| GSM7666364 |
EC-3h, replicate 1, scRNA-seq |
| GSM7666365 |
EC-3h, replicate 2, scRNA-seq |
| GSM7666366 |
PA-biofilm, replicate 1, scRNA-seq |
| GSM7666367 |
PA-biofilm, replicate 2, scRNA-seq |
| GSM7666368 |
PA-biofilm-ΔΔ, replicate 1, scRNA-seq |
| GSM7666369 |
PA-biofilm-ΔΔ, replicate 2, scRNA-seq |
| GSM7666370 |
SA-3h, replicate 1, scRNA-seq |
| GSM7666371 |
SA-3h, replicate 2, scRNA-seq |
| GSM7666372 |
SA-3h-ΔΔ-replicate 1, scRNA-seq |
| GSM7666373 |
SA-3h-ΔΔ-replicate 2, scRNA-seq |
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| This SuperSeries is composed of the following SubSeries: |
| GSE239502 |
Bacterial single cell RNA-seq unveils cyclic-di-GMP as an antitoxin critical for antibiotic tolerance in biofilm [ChIP-seq] |
| GSE239503 |
Bacterial single cell RNA-seq unveils cyclic-di-GMP as an antitoxin critical for antibiotic tolerance in biofilm [RNA-seq] |
| GSE239504 |
Bacterial single cell RNA-seq unveils cyclic-di-GMP as an antitoxin critical for antibiotic tolerance in biofilm [scRNA-seq] |
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| Relations |
| BioProject |
PRJNA999599 |
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