|
| Status |
Public on Aug 02, 2023 |
| Title |
Decitabine disrupts EBV genomic epiallele DNA methylation patterns around CTCF binding sites to increase chromatin accessibility and lytic transcription in gastric cancer [ATAC] |
| Organism |
human gammaherpesvirus 4 |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
To investigate the EBV genome after Decitabine treatment by reduced representation bisulfite sequencing, ATAC-seq, and RNA-seq
|
| |
|
| Overall design |
Two EBV positive gastric cancer cell lines were treated with decitabine for 1 and 3 days and ATAC-seq was performed
|
| |
|
| Contributor(s) |
Tempera I, Leiberman PM |
| Citation(s) |
37606370 |
| Submission date |
Jul 31, 2023 |
| Last update date |
Dec 07, 2023 |
| Contact name |
Priyankara J Wickramasinghe |
| E-mail(s) |
priyaw@wistar.org
|
| Phone |
2154956837
|
| Organization name |
The Wistar Institute
|
| Department |
Bioinformatics
|
| Lab |
Genomics
|
| Street address |
3601 Spruce Street
|
| City |
Philadelphia |
| State/province |
PA |
| ZIP/Postal code |
19104 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL33481 |
Illumina NextSeq 500 (Human gammaherpesvirus 4) |
|
| Samples (12)
|
|
| This SubSeries is part of SuperSeries: |
| GSE239770 |
Decitabine disrupts EBV genomic epiallele DNA methylation patterns around CTCF binding sites to increase chromatin accessibility and lytic transcription in gastric cancer |
|
| Relations |
| BioProject |
PRJNA1000476 |
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