NCBI Logo
GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
          Go
Series GSE239695 Query DataSets for GSE239695
Status Public on Mar 14, 2024
Title Tumor DNA methylation profiling of patients with Adamantinomatous craniopharyngioma (ACP)
Organism Homo sapiens
Experiment type Methylation profiling by genome tiling array
Summary Abnormal DNA methylation plays a role in tumor progression and is becoming recognized as a prognostic marker in various types of cancers. In this study, we aimed to investigate the association between DNA methylation and clinicopathological features, prognosis, and outcomes in patients with Adamantinomatous craniopharyngioma (ACPs). To achieve this, we analyzed the global methylation profile of 35 tumors using the Illumina Infinium HumanMethylation850 BeadChip.
 
Overall design DNA from 35 microdissected, fresh frozen tumor samples from was extracted using the QIAamp DNA Mini Kit (QIAGEN, Hilden, Germany) according to the manufacturer's instruction. DNA was commisioned to the University of Southern California Keck Genomics Platform (Los Angeles, CA, USA), where it was bisulfite-converted using tht EZ DNA methylation kit (Zymo Research, Irvine, CA) , as provided by the manufacturer, and hybridized to the Illumina Infinium HumanMethylation850 BeadChip as specified by Illumina.
 
Contributor(s) Gutiérrez JM, Bueno AC, Martins CS, de Castro M
Citation(s) 38181427
Submission date Jul 31, 2023
Last update date Mar 15, 2024
Contact name Junier Marrero Gutiérrez
E-mail(s) jmarreroguti@alumni.usp.br
Phone +5516-39636623
Organization name Ribeirão Preto Medical School-University of São Paulo
Department Pediatric
Lab Molecular Endocrinology
Street address Av Bandeirantes, 3900
City Ribeirão Preto
State/province São Paulo
ZIP/Postal code 14049-900
Country Brazil
 
Platforms (1)
GPL23976 Illumina Infinium HumanMethylation850 BeadChip
Samples (35)
GSM7670077 Tumor DNA from adamantinomatous craniopharyngioma Tumor 015
GSM7670078 Tumor DNA from adamantinomatous craniopharyngioma Tumor 016
GSM7670079 Tumor DNA from adamantinomatous craniopharyngioma Tumor 019
Relations
BioProject PRJNA1000583

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE239695_Matrix_Signal_Intensity.csv.gz 173.4 Mb (ftp)(http) CSV
GSE239695_RAW.tar 490.9 Mb (http)(custom) TAR (of IDAT)
Processed data included within Sample table

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap
External link. Please review our privacy policy.