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Status |
Public on Aug 05, 2023 |
Title |
Single-nucleus transcriptional profiling of chronic kidney disease after cisplatin nephrotoxicity |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
Cisplatin induces both acute and chronic nephrotoxicity during chemotherapy in cancer patients. Here, we report the study of single-nucleus sequencing (snRNA-seq) of cisplatin-induced nephrotoxicity.
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Overall design |
Male C57BL/6 mice were given 4 consecutive weekly injections of 8 mg/kg cisplatin. Kidney tissues were collected at 9 weeks after the first cisplatin injection for single-nucleus RNA sequencing (snRNA-seq)
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Web link |
https://pubmed.ncbi.nlm.nih.gov/35092726/
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Contributor(s) |
Ma Z, Hu X, Ding H, Dong Z |
Citation(s) |
35092726 |
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Submission date |
Aug 01, 2023 |
Last update date |
Nov 28, 2023 |
Contact name |
Zhengwei Ma |
E-mail(s) |
zma@augusta.edu
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Organization name |
Augusta University
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Street address |
1460 Laney walker Blvd.
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City |
Augusta |
State/province |
GA |
ZIP/Postal code |
30912 |
Country |
USA |
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Platforms (1) |
GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
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Samples (4)
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Relations |
BioProject |
PRJNA1000910 |