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| Status |
Public on May 16, 2024 |
| Title |
Transcriptional profiles of venous and lymphatic endothelial cells from tie1 mutant zebrafish |
| Organism |
Danio rerio |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
To investigate what kind of gene expression is regulated downstream of Tie1 signaling, we performed RNA-seq analyses on venous and lymphatic endothelial cells (ECs) between homozygous tie1 mutant embryos and their wild-type and heterozygous siblings during secondary sprouting, respectively. Our analyses indicate that Tie1 signaling controls a series of gene expression involved in lymphatic development including EC migration, proliferation, and differentiation.
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for endothelial cells from homozygous tie1 mutant embryos and their wild-type and heterozygous siblings in zebrafish.
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| Contributor(s) |
Morooka N, Mochizuki N, Nakajima H |
| Citation(s) |
38742432 |
| |
| Submission date |
Aug 08, 2023 |
| Last update date |
May 17, 2024 |
| Contact name |
Hiroyuki Nakajima |
| E-mail(s) |
nakajima@ncvc.go.jp
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| Phone |
+81-6-6170-1070
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| Organization name |
National Cerebral and Cardiovascular Center Research Institute
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| Department |
Department of Cell Biology
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| Street address |
6-1 Kishibeshinmachi
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| City |
Suita |
| State/province |
Osaka |
| ZIP/Postal code |
564-8565 |
| Country |
Japan |
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| Platforms (1) |
| GPL20828 |
Illumina NextSeq 500 (Danio rerio) |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA1003386 |
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