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Series GSE241250 Query DataSets for GSE241250
Status Public on Oct 01, 2023
Title Transcriptome analysis of Bacillus cereus strain INRA C3 in response to iron depletion and lactoferrin, accomplished by RNA sequencing
Organism Bacillus cereus
Experiment type Expression profiling by high throughput sequencing
Summary The iron-binding glycoprotein lactoferrin exhibits anti-bacterial activity. To investigate the overall response of Bacillus cereus to lactoferrin, total transcriptome analyses were performed. Growth conditions were mMOD minimal medium, minimal medium plus 10 mg/ml lactoferrin, as well as minimal medium without iron source for comparison. Differential regulation of genes involved in iron acquisition as well as genes encoding enterotoxins and further virulence factors was of special interest.
Overall design For subsequent RNA sequencing, strain INRA C3 was grown for two hours in mMOD minimal medium, mMOD-Fe (without iron source) and mMOD supplemetned with 10 mg/ml lactoferrin. Two biological replicates were prepared per growth condition.
Contributor(s) Jugert C, Didier A, Jessberger N
Citation(s) 38029127
Submission date Aug 21, 2023
Last update date Dec 06, 2023
Contact name Nadja Jessberger
Organization name University of Veterinary Medicine Hannover, Foundation
Department Institute for Food Quality and Food Safety
Street address Bischofsholer Damm 15
City Hannover
ZIP/Postal code 30173
Country Germany
Platforms (1)
GPL26265 Illumina HiSeq 2500 (Bacillus cereus)
Samples (6)
GSM7720017 B. cereus, MOD, Rep a
GSM7720018 B. cereus, MOD, Rep b
GSM7720019 B. cereus, MOD-Fe, Rep a
BioProject PRJNA1007588

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SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE241250_MOD_FE_vs_LF10.DE.tsv.gz 155.6 Kb (ftp)(http) TSV
GSE241250_MOD_Fe_vs_LF10_22.08.22.xlsx 310.4 Kb (ftp)(http) XLSX
GSE241250_MOD_vs_LF10.DE.tsv.gz 155.1 Kb (ftp)(http) TSV
GSE241250_MOD_vs_LF10_22.08.22.xlsx 309.3 Kb (ftp)(http) XLSX
GSE241250_MOD_vs_MOD_FE.DE.tsv.gz 135.8 Kb (ftp)(http) TSV
GSE241250_MOD_vs_MOD_Fe_22.08.22.xlsx 279.5 Kb (ftp)(http) XLSX
GSE241250_NG-27598.profiling-annotation.gff.gz 323.1 Kb (ftp)(http) GFF
GSE241250_NG-27598.profiling-normalized.gct.gz 249.7 Kb (ftp)(http) GCT
GSE241250_NG-27598.profiling-raw.gct.gz 113.2 Kb (ftp)(http) GCT
GSE241250_NG-27598.profiling-stats.txt.gz 279 b (ftp)(http) TXT
GSE241250_NG-27598.profiling-table.txt.gz 278.3 Kb (ftp)(http) TXT
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Processed data are available on Series record

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