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| Status |
Public on May 22, 2024 |
| Title |
DCAF15 control of cohesin dynamics sustains acute myeloid leukemia |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
This SuperSeries is composed of the SubSeries listed below.
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| Overall design |
Refer to individual Series
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| Web link |
https://www.nature.com/articles/s41467-024-49882-x
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| Contributor(s) |
Grothusen GP, Chang R, Zhou N, Wulfridge P, Sarma K, Busino L |
| Citation(s) |
38961054 |
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| Submission date |
Aug 23, 2023 |
| Last update date |
Jul 04, 2024 |
| Contact name |
Luca Busino |
| E-mail(s) |
businol@upenn.edu
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| Phone |
215-746-2569
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| Organization name |
University of Pennsylvania
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| Department |
Cancer Biology
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| Lab |
Luca Busino Laboratory
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| Street address |
421 Curie Boulevard
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| City |
Philadelphia |
| State/province |
Pennsylvania |
| ZIP/Postal code |
19104 |
| Country |
USA |
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| Platforms (2) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
| GPL30173 |
NextSeq 2000 (Homo sapiens) |
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| Samples (36)
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| GSM7731230 |
MV4-11 cells, LRG2.1-sgROSA26(Control), LRCherry2.1-sgROSA26(Control), rep1 |
| GSM7731231 |
MV4-11 cells, LRG2.1-sgROSA26(Control), LRCherry2.1-sgROSA26(Control), rep2 |
| GSM7731232 |
MV4-11 cells, LRG2.1-sgROSA26(Control), LRCherry2.1-sgROSA26(Control), rep3 |
| GSM7731233 |
MV4-11 cells, LRG2.1-sgROSA26(Control), LRCherry2.1-sgDCAF15#2, rep1 |
| GSM7731234 |
MV4-11 cells, LRG2.1-sgROSA26(Control), LRCherry2.1-sgDCAF15#2, rep2 |
| GSM7731235 |
MV4-11 cells, LRG2.1-sgROSA26(Control), LRCherry2.1-sgDCAF15#2, rep3 |
| GSM7731236 |
MV4-11 cells, LRG2.1-sgTP53#6, LRCherry2.1-sgROSA26(Control), rep1 |
| GSM7731237 |
MV4-11 cells, LRG2.1-sgTP53#6, LRCherry2.1-sgROSA26(Control), rep2 |
| GSM7731238 |
MV4-11 cells, LRG2.1-sgTP53#6, LRCherry2.1-sgROSA26(Control), rep3 |
| GSM7731239 |
MV4-11 cells, LRG2.1-sgTP53#6, LRCherry2.1-sgDCAF15#2, rep1 |
| GSM7731240 |
MV4-11 cells, LRG2.1-sgTP53#6, LRCherry2.1-sgDCAF15#2, rep2 |
| GSM7731241 |
MV4-11 cells, LRG2.1-sgTP53#6, LRCherry2.1-sgDCAF15#2, rep3 |
| GSM7731242 |
HEL cells, LRCherry2.1-sgROSA26(Control), rep1 |
| GSM7731243 |
HEL cells, LRCherry2.1-sgROSA26(Control), rep2 |
| GSM7731244 |
HEL cells, LRCherry2.1-sgROSA26(Control), rep3 |
| GSM7731245 |
HEL cells, LRCherry2.1-sgDCAF15#2, rep1 |
| GSM7731246 |
HEL cells, LRCherry2.1-sgDCAF15#2, rep2 |
| GSM7731247 |
HEL cells, LRCherry2.1-sgDCAF15#2, rep3 |
| GSM7731248 |
HEL cells, LRCherry2.1-sgROSA26(Control), Input |
| GSM7731249 |
HEL cells, LRCherry2.1-sgROSA26(Control), total-SMC3, ChIP |
| GSM7731250 |
HEL cells, LRCherry2.1-sgROSA26(Control), acetyl-SMC3, ChIP |
| GSM7731251 |
HEL cells, LRCherry2.1-sgDCAF15#2, total-SMC3, ChIP |
| GSM7731252 |
HEL cells, LRCherry2.1-sgDCAF15#2, acetyl-SMC3, ChIP |
| GSM7731253 |
HEL cells, LRCherry2.1-sgROSA26(Control), rep1 |
| GSM7731254 |
HEL cells, LRCherry2.1-sgROSA26(Control), rep2 |
| GSM7731255 |
HEL cells, LRCherry2.1-sgDCAF15#2, rep1 |
| GSM7731256 |
HEL cells, LRCherry2.1-sgDCAF15#2, rep2 |
| GSM8239382 |
OCI-AML3 cells, Nt_FLAG-HA-FKBP12(F36V)_DCAF15, DMSO (Control), rep1 |
| GSM8239383 |
OCI-AML3 cells, Nt_FLAG-HA-FKBP12(F36V)_DCAF15, DMSO (Control), rep2 |
| GSM8239384 |
OCI-AML3 cells, Nt_FLAG-HA-FKBP12(F36V)_DCAF15, DMSO (Control), rep3 |
| GSM8239385 |
OCI-AML3 cells, Nt_FLAG-HA-FKBP12(F36V)_DCAF15, dTAGv1_24h, rep1 |
| GSM8239386 |
OCI-AML3 cells, Nt_FLAG-HA-FKBP12(F36V)_DCAF15, dTAGv1_24h, rep2 |
| GSM8239387 |
OCI-AML3 cells, Nt_FLAG-HA-FKBP12(F36V)_DCAF15, dTAGv1_24h, rep3 |
| GSM8239388 |
OCI-AML3 cells, Nt_FLAG-HA-FKBP12(F36V)_DCAF15, dTAGv1_72h, rep1 |
| GSM8239389 |
OCI-AML3 cells, Nt_FLAG-HA-FKBP12(F36V)_DCAF15, dTAGv1_72h, rep2 |
| GSM8239390 |
OCI-AML3 cells, Nt_FLAG-HA-FKBP12(F36V)_DCAF15, dTAGv1_72h, rep3 |
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| This SuperSeries is composed of the following SubSeries:
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| GSE241578 |
CRL4-DCAF15 control of cohesin dynamics sustains cell proliferation [RNA-seq_CRISPR] |
| GSE241579 |
CRL4-DCAF15 control of cohesin dynamics sustains cell proliferation [ChIP-seq] |
| GSE241580 |
CRL4-DCAF15 control of cohesin dynamics sustains cell proliferation [HiC] |
| GSE266010 |
CRL4-DCAF15 control of cohesin dynamics sustains cell proliferation [RNA-seq_dTAG] |
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| Relations |
| BioProject |
PRJNA1008723 |
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