|
| Status |
Public on Oct 12, 2010 |
| Title |
Transcriptional profiling of the acuM null mutant |
| Platform organism |
Aspergillus fumigatus Af293 |
| Sample organism |
Aspergillus fumigatus |
| Experiment type |
Expression profiling by array
|
| Summary |
Deletion of AcuM caused attenuated virulence in mouse models of Aspergillosis, we carried out the microarry to figure out pathways have been changed to affect the virulence.
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| |
|
| Overall design |
Transcriptional profiling of Aspergillus fumigatus mycelium comparing mutant ΔacuM with wild type Af293, and complemented strain ΔacuM ::acuM with mutant ΔacuM . Three time points comparison under RPMI: 8 hour, 18 hour, 24 hour. Biological replicates: 2, independently grown and harvest. One replicate per array.
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| |
|
| Contributor(s) |
Filler SG, Liu H, Chen D, Nierman WC |
| Citation(s) |
21062375 |
| |
| Submission date |
Sep 30, 2010 |
| Last update date |
Mar 22, 2012 |
| Contact name |
Natalie Fedorova |
| E-mail(s) |
natalief@jcvi.org
|
| Phone |
301-795-7756
|
| Fax |
301-838-0208
|
| Organization name |
JCVI
|
| Department |
Infectious Disease
|
| Street address |
9704 Medical Center Dr
|
| City |
Rockville |
| State/province |
MD |
| ZIP/Postal code |
20850 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL10341 |
JCVI Aspergillus fumigatus AF293 29.9K amplicon array |
|
| Samples (12)
|
| GSM602685 |
Af293 vs. ΔacuM 8 hour Replicate 1 |
| GSM602686 |
Af293 vs. ΔacuM 8 hour Replicate 2 |
| GSM602687 |
Af293 vs. ΔacuM 18 hour Replicate 1 |
| GSM602688 |
Af293 vs. ΔacuM 18 hour Replicate 2 |
| GSM602689 |
Af293 vs. ΔacuM 24 hour Replicate 1 |
| GSM602690 |
Af293 vs. ΔacuM 24 hour Replicate 2 |
| GSM602691 |
ΔacuM vs. ΔacuM ::acuM 8 hour Replicate 1 |
| GSM602692 |
ΔacuM vs. ΔacuM ::acuM 8 hour Replicate 2 |
| GSM602693 |
ΔacuM vs. ΔacuM ::acuM 18 hour Replicate 1 |
| GSM602694 |
ΔacuM vs. ΔacuM ::acuM 18 hour Replicate 2 |
| GSM602695 |
ΔacuM vs. ΔacuM ::acuM 24 hour Replicate 1 |
| GSM602696 |
ΔacuM vs. ΔacuM ::acuM 24 hour Replicate 2 |
|
| Relations |
| BioProject |
PRJNA132761 |
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