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| Status |
Public on Oct 25, 2024 |
| Title |
Gene sequencing of taste bud tissue in rat tongue epithelium |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Purposes: To investigate the effect of periodontitis on taste sensitivity through RNA sequencing
Methods: Three chronic periodontitis rats and non-periodontitis rats were selected for circumvallate papilla, and RNA sequencing was performed on Illumina NexSeq
Results: If P ≤ 0.05, fold change ≥ 1.5 as the cut off, 21 differential genes were up-regulated and 74 were down-regulated。 KEGG analyzed 4 up-regulated and 8 down-regulated expression pathways.
Conclusion: There were 21 up-regulated differential genes and 74 down-regulated differential genes in rat circumvallate papilla tissue samples.
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| Overall design |
Gene sequencing of circumvallate papilla tissue in periodontitis rats and non-periodontitis rats
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| |
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| Contributor(s) |
Gao S, Zhou Q, Zhang B |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Oct 25, 2023 |
| Last update date |
Oct 25, 2024 |
| Contact name |
Qiaozhen Zhou |
| E-mail(s) |
quhd21@lzu.edu.cn
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| Organization name |
Lanzhou University
|
| Department |
School/Hospital of Stomatology Lanzhou University
|
| Street address |
No.199 Donggang West Road
|
| City |
Lanzhou |
| ZIP/Postal code |
730000 |
| Country |
China |
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| Platforms (1) |
| GPL25947 |
Illumina NovaSeq 6000 (Rattus norvegicus) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA1031972 |
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