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Status |
Public on Nov 06, 2023 |
Title |
Allometry of cell types in planarians by single cell transcriptomics |
Organism |
Schmidtea mediterranea |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
We used scRNA-seq to examine cell type allometry in asexual planarians. We profiled 28,738 single cell transcriptomes of planarian of 3 different sizes categories: small (S), medium (M) and large (L). We detected changes in cell type frequency and gene expression patterns in planarian of different sizes, capturing regulatory programs of distinct cell types in response to allometric scaling.
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Overall design |
We obtained cell dissociations from adult populations of the asexual strain of Schmidtea mediterranea of different body sizes.
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Contributor(s) |
Emili E, Pérez-Posada A, Christodoulou M, Solana J |
Citation missing |
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Submission date |
Oct 31, 2023 |
Last update date |
Nov 06, 2023 |
Contact name |
Jordi Solana |
E-mail(s) |
scbe.lab@gmail.com
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Organization name |
University of Exeter
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Department |
Health and Life Sciences
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Street address |
Northcote House
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City |
Exeter |
ZIP/Postal code |
EX4 4QD |
Country |
United Kingdom |
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Platforms (1) |
GPL29967 |
Illumina NovaSeq 6000 (Schmidtea mediterranea) |
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Samples (2) |
GSM7874574 |
Schmidtea mediterranea, whole-body, scRNA-seq, batch 1, library 15_5_shallow, library 23_1_deep |
GSM7874575 |
Schmidtea mediterranea, whole-body, scRNA-seq, batch 1, library 15_6_shallow, library 23_2_deep |
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Relations |
BioProject |
PRJNA1034119 |
Supplementary file |
Size |
Download |
File type/resource |
GSE246681_barcodes.tsv.gz |
226.7 Kb |
(ftp)(http) |
TSV |
GSE246681_features.tsv.gz |
212.8 Kb |
(ftp)(http) |
TSV |
GSE246681_matrix.mtx.gz |
23.7 Mb |
(ftp)(http) |
MTX |
SRA Run Selector |
Raw data are available in SRA |
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