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| Status |
Public on Aug 14, 2024 |
| Title |
Multiomics analysis of canine myocardium after circumferential pulmonary vein ablation: Effect of NPY on long-term reinduction of atrial fibrillation |
| Organism |
Canis lupus familiaris |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
In this study,We established a long-term model of beagle canines after circumferential pulmonary vein ablation (CPVA). The transcriptome and proteome were obtained using high-throughput sequencing and TMT-tagged LC‒MS/LC analysis. Differentially expressed genes and proteins were screened and enriched, and the effect of fibrosis was found and verified in tissues
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| Overall design |
Beagles underwent thoracotomy in the right fourth intercostal space, followed by circumferential pulmonary vein catheter ablation(CPVA). After 6 months of feeding, bullseye atrial muscle tissues were collected (CPVA:Control=5:5).
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| Contributor(s) |
Hou Y, Du J, Song Q |
| Citation(s) |
39107876 |
| |
| Submission date |
Nov 20, 2023 |
| Last update date |
Aug 14, 2024 |
| Contact name |
Yinglong Hou |
| E-mail(s) |
yinglonghou@hotmail.com
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| Organization name |
Qianfoshan Hospital of Shandong Province
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| Street address |
No. 16766, Jingshi Road, Lixia District, Jinan City, Shandong Province, China
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| City |
Jinan |
| State/province |
ShanDong |
| ZIP/Postal code |
250000 |
| Country |
China |
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| Platforms (1) |
| GPL33670 |
DNBSEQ-T7 (Canis lupus familiaris) |
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| Samples (10)
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| Relations |
| BioProject |
PRJNA1043163 |
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