 |
 |
GEO help: Mouse over screen elements for information. |
|
| Status |
Public on Dec 01, 2023 |
| Title |
Spatial transcriptomics reveals the pharmacological effects on tumors and TME structural heterogeneity under MASK vaccine treatment |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To explore the pharmacological effects on tumors and TME structural heterogeneity under Magnetic Sculpture-liKe (MASK) Cells vaccine treatment, we performed spatial transcriptomics (ST) with B16F10 xenograft receiving MASK vaccine and magnet treatment.
|
| |
|
| Overall design |
C57BL/6 mice subcutaneously inoculated with B16-F10-Luciferase cells were randomly divided into two groups: PBS and MASK. Sample MASK1 was collected on the 7 days after MASK vaccine treatment, Sample MASK2 was collected on the 13 days after MASK vaccine treatment. Magnet processing group according to the previous method. After the treatment periods, tumor samples were collected, and spatial transcriptomics was performed.
|
| |
|
| Contributor(s) |
Li Q, Zhang H, Wang K, Cheng S |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Nov 21, 2023 |
| Last update date |
Dec 01, 2023 |
| Contact name |
Heng Zhang |
| E-mail(s) |
zhangheng043@mail.nankai.edu.cn
|
| Organization name |
Nankai University
|
| Street address |
38 Rd.Tongyan
|
| City |
Tianjin |
| ZIP/Postal code |
300350 |
| Country |
China |
| |
|
| Platforms (1) |
|
| Samples (3) |
|
| Relations |
| BioProject |
PRJNA1043581 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE248356_RAW.tar |
157.5 Mb |
(http)(custom) |
TAR (of CSV, JPG, JSON, MTX, PNG, TSV) |
SRA Run Selector |
| Raw data are available in SRA |
|
|
|
|
 |
