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| Status |
Public on Oct 27, 2010 |
| Title |
Gene expression profiling of CD34+ subsets in Multiple Myeloma and healthy individuals |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Multiple myeloma (MM) is a clonal plasma cell disorder frequently accompanied by hematopoietic impairment. Genomic profiling of distinct HSPC subsets revealed a consistent deregulation of signaling cascades, including TGF beta signaling, p38MAPK signaling and pathways involved in cytoskeletal organization, migration, adhesion and cell cycle regulation in MM patients.
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| |
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| Overall design |
CD34+ subsets of 7 patients with Multiple Myeloma and 5 healthy volunteers were analysed by means of gene expression profiling with the Affymetrix HU-133A 2.0 array
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| |
|
| Contributor(s) |
Bruns I |
| Citation(s) |
22517906 |
| |
| Submission date |
Oct 21, 2010 |
| Last update date |
Dec 06, 2018 |
| Contact name |
Ingmar Bruns |
| E-mail(s) |
BrunsIn@med.uni-duesseldorf.de
|
| Phone |
+49-211-81-17736
|
| Fax |
+49-211-81-18853
|
| Organization name |
University of Düsseldorf
|
| Department |
Hematology, Oncology and Clinical Immunology
|
| Lab |
Experimental Hematology
|
| Street address |
Moorenstr. 5
|
| City |
Düsseldorf |
| State/province |
NRW |
| ZIP/Postal code |
40225 |
| Country |
Germany |
| |
|
| Platforms (1) |
| GPL571 |
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array |
|
| Samples (43)
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| Relations |
| BioProject |
PRJNA132127 |
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