|
| Status |
Public on Dec 31, 2023 |
| Title |
Liver transcriptome of an LPS infusion model for porcine sepsis |
| Organism |
Sus scrofa |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Sepsis is a life-threatening organ dysfunction resulting from a dysregulated host response to infection. This is best studied in humans and various mouse models, however finding sof these models to not always translate easy to the clinic. In order to improve this transfer, and because sepsis also plays a significant role in vetrenairy medicine, we use the pig as a model organism in sepsis research. We compare two modes of porcine sepsis iduction: fecal infusion and LPS infusion and also compare thse o wha we can find in mice
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| |
|
| Overall design |
2 conditions LPS and PBS (controls) each with 3 biological replicates
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| |
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| Contributor(s) |
Halimi F, Vanderhaeghen T, Timmermans S, Garcia B, Vandewalle J, Herpain A, Dhont L, Croubels S, Libert C |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Dec 12, 2023 |
| Last update date |
Dec 31, 2023 |
| Contact name |
Steven Timmermans |
| Organization name |
VIB-UGent
|
| Street address |
Technologiepark 71
|
| City |
Gent |
| ZIP/Postal code |
9052 |
| Country |
Belgium |
| |
|
| Platforms (1) |
| GPL26351 |
Illumina NovaSeq 6000 (Sus scrofa) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA1051645 |
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