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Status |
Public on Feb 05, 2024 |
Title |
HeLa, Gene expression under normoxia (20%) vs hypoxia (<0.1% oxygen) |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
Hypoxic cancer cells are known to acquire malignance like invasiveness and therapy resistance. In order to identify the candidate genes responsible for the malignant properties of hypoxic cancer cells, gene expression profile of hypoxic cancer cells is investigated herein.
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Overall design |
To characterise the genes that are related to malignance and simultaneously can be induced under hypoxia, total RNA samples from HeLa cells cultured under severely hypoxic conditions (<0.1% oxygen) and under normoxic conditions (20% oxygen) were subjected to RNA sequencing. Gene expression profiles of normoxic and hypoxic cells were compared in order to identify the relevant differentially expressed genes.
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Contributor(s) |
Lee PW, Chow CC, Kobayashi M, Harada H |
Citation(s) |
38740970 |
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Submission date |
Jan 29, 2024 |
Last update date |
Aug 02, 2024 |
Contact name |
Peter Wai Tik LEE |
Organization name |
Kyoto University
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Department |
Graduate School of Biostudies
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Lab |
Laboratory of Cancer Cell Biology
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Street address |
Sakyo Ward, Yoshidakonoecho
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City |
Kyoto |
ZIP/Postal code |
606-8501 |
Country |
Japan |
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Platforms (1) |
GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
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Samples (2) |
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Relations |
BioProject |
PRJNA1070641 |