NCBI Logo
GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
          Go
Series GSE254480 Query DataSets for GSE254480
Status Public on Feb 05, 2024
Title HeLa, Gene expression under normoxia (20%) vs hypoxia (<0.1% oxygen)
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Hypoxic cancer cells are known to acquire malignance like invasiveness and therapy resistance. In order to identify the candidate genes responsible for the malignant properties of hypoxic cancer cells, gene expression profile of hypoxic cancer cells is investigated herein.
 
Overall design To characterise the genes that are related to malignance and simultaneously can be induced under hypoxia, total RNA samples from HeLa cells cultured under severely hypoxic conditions (<0.1% oxygen) and under normoxic conditions (20% oxygen) were subjected to RNA sequencing. Gene expression profiles of normoxic and hypoxic cells were compared in order to identify the relevant differentially expressed genes.
 
Contributor(s) Lee PW, Chow CC, Kobayashi M, Harada H
Citation(s) 38740970
Submission date Jan 29, 2024
Last update date Aug 02, 2024
Contact name Peter Wai Tik LEE
Organization name Kyoto University
Department Graduate School of Biostudies
Lab Laboratory of Cancer Cell Biology
Street address Sakyo Ward, Yoshidakonoecho
City Kyoto
ZIP/Postal code 606-8501
Country Japan
 
Platforms (1)
GPL18573 Illumina NextSeq 500 (Homo sapiens)
Samples (2)
GSM8043001 HeLa_Normoxia
GSM8043002 HeLa_Hypoxia
Relations
BioProject PRJNA1070641

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE254480_RAW.tar 30.0 Kb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap
External link. Please review our privacy policy.