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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Feb 26, 2024 |
| Title |
Expression profiling of microRNAs in mouse livers with deletion of paternally-expressed, imprinted Mir483 [miRNA-seq] |
| Organism |
Mus musculus |
| Experiment type |
Non-coding RNA profiling by high throughput sequencing
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| Summary |
In this study we generated mice with constitutive deletion of microRNA Mir483, which is imprinted and expressed from the paternal allele only. Global analysis of microRNA expression was performed by miRNA-seq in livers collected from E18.5 fetuses (mutants with deletion of paternal allele - Mir483Pat-KO - and wild-type controls).
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| Overall design |
We performed miRNA-seq analysis in E18.5 mouse livers of female fetuses with deletion of paternally-expressed microRNA Mir483 (n=7 biological replicates) and wild-type littermate controls (n=5 biological replicates)
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| Contributor(s) |
Sandovici I, Lam B, Constancia M |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Feb 21, 2024 |
| Last update date |
Feb 26, 2024 |
| Contact name |
Brian Yee Hong Lam |
| E-mail(s) |
yhbl2@cam.ac.uk
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| Organization name |
University of Cambridge
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| Department |
Metabolic Research Laboratories
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| Street address |
Box 289 Addenbookes Hospital, Hills Road
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| City |
Cambridge |
| ZIP/Postal code |
CB2 0QQ |
| Country |
United Kingdom |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (12)
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| GSM8093372 |
Liver, wild-type, rep4 (miRNA-seq) |
| GSM8093373 |
Liver, wild-type, rep5 (miRNA-seq) |
| GSM8093374 |
Liver, Mir483Pat-KO, rep1 (miRNA-seq) |
| GSM8093375 |
Liver, Mir483Pat-KO, rep2 (miRNA-seq) |
| GSM8093376 |
Liver, Mir483Pat-KO, rep3 (miRNA-seq) |
| GSM8093377 |
Liver, Mir483Pat-KO, rep4 (miRNA-seq) |
| GSM8093378 |
Liver, Mir483Pat-KO, rep5 (miRNA-seq) |
| GSM8093379 |
Liver, Mir483Pat-KO, rep6 (miRNA-seq) |
| GSM8093380 |
Liver, Mir483Pat-KO, rep7 (miRNA-seq) |
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| Relations |
| BioProject |
PRJNA1078899 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE256305_miR.Counts.csv.gz |
18.1 Kb |
(ftp)(http) |
CSV |
SRA Run Selector |
| Raw data are available in SRA |
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