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| Status |
Public on Jul 01, 2011 |
| Title |
High-frequency stimulation of the ventrolateral thalamus regulates gene expression in hippocampus, motor cortex and caudate-putamen |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
|
| Summary |
Transcriptional profiling of rat hippocampus comparing rats subjected to chronic (1 hour daily during 14 days) vetrolateral thalamus stimulation (DBS group) with sham operated rats (with electrode placement but without stimulation) and with naive rats.
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| Overall design |
Three-condition experiment, DBS, sham and naive. Every sample consisted of pooled hippocampi from three rats. Slices between Bregma levels -2 and -4 were used for dissections of the hippocampi. Common reference design, comparing every condition versus a brain pooled tissue consisting of pooled hippocampal, thalamic and cortical brain tissue of the naive (n=4), sham-operated (n=5) and stimulated (n=4) rats. Biological replicates: 4 DBS, 4 sham and 3 naive. One replicate per array.
Deep brain stimulation
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| Contributor(s) |
Huguet G, Kádár E |
| Citation(s) |
21458429 |
| |
| Submission date |
Dec 06, 2010 |
| Last update date |
Mar 22, 2012 |
| Contact name |
Gemma Huguet |
| E-mail(s) |
gemma.huguet@udg.edu
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| Organization name |
Universitat de Girona
|
| Street address |
Campus de Montilivi
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| City |
Girona |
| ZIP/Postal code |
17071 |
| Country |
Spain |
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| Platforms (1) |
| GPL11280 |
Agilent-024196 Whole Rat Genome Microarray 4x44K (Feature Number version) |
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| Samples (11)
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| Relations |
| BioProject |
PRJNA135783 |
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