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| Status |
Public on Dec 14, 2010 |
| Title |
Agilent_E. coli O157 response to Chrysanthemum herba |
| Organism |
Escherichia coli |
| Experiment type |
Expression profiling by array
|
| Summary |
According to our study, Chrysanthemum lavandulifolum extract showed excellent antibiotic effects on Escherichia coli O157:H7. A notable point is that the antibiotic efficacy of the herb extract is on the all three proven targets for main antibiotic drugs that are bacterial cell wall biosynthesis, bacterial protein synthesis and bacterial DNA replication and repair. This multi-target efficacy of the herbal antibiotics may be used as more effective and safe drugs that substitute existing antibiotics.
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| Overall design |
Up- or downregulated gene expressions in E. coli O157:H7 (EDL932) which exposure to Chrysanthemum lavandulifolum (CL) methyl chloride (MC) fraction for 24 hours was measured.
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| Contributor(s) |
Kim K, Jang H |
| Citation(s) |
23255247 |
| |
| Submission date |
Dec 11, 2010 |
| Last update date |
Jan 09, 2013 |
| Contact name |
Ki-Suk Kim |
| E-mail(s) |
seridy@naver.com
|
| Organization name |
University of Colorado Anschutz Medical Campus
|
| Department |
Pediatrics
|
| Street address |
12801 E 17th Ave
|
| City |
Aurora |
| State/province |
CO |
| ZIP/Postal code |
80045 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL8984 |
Biodesign Inst. at ASU Escherichia coli Agilent-020097 array |
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| Samples (1) |
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| Relations |
| BioProject |
PRJNA135481 |
