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| Status |
Public on Jul 04, 2005 |
| Title |
Gene expression profiling of children affected by acute lymphoblastic leukemia |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
We have examined gene expression profiling of 18 children with acute lymphoblastic leukemia (ALL). In particular, the ALL patients are subdivided in three different subtypes by morphological, immunophenotypic and cytogenetical parameters: 10 ALL-B, 5 ALL-T and 3 ALL-B with the specific chromosomal aberration MLL/AF4. We compared the transcription profiles of the leukemic samples by microarray competitive hybridization against an arbitrary total RNA reference prepared from normal human bone marrow. Two replicates of each experiment were done using different microarray slides, in which the sample and reference RNAs labeled either with Cy3 or Cy5 fluorochromes were crossed in both combinations.
ALL-B patients: GSM49966, GSM49967, GSM49969, GSM49970, GSM49971, GSM49972, GSM49973, GSM49974, GSM49976, GSM49977, GSM49978, GSM49979, GSM49980, GSM49981, GSM49982, GSM49983, GSM49984, GSM49985, GSM49986, GSM49987
ALL-T patients: GSM49988, GSM49989, GSM49990, GSM49991, GSM49992, GSM49993, GSM49994, GSM49995, GSM49996, GSM49997
ALL-B patients with the specific chromosomal aberration MLL/AF4: GSM49999, GSM50001, GSM50004, GSM50005, GSM50006, GSM50007
Keywords = Acute lymphoblastic leukemia (ALL)
Keywords = human bone marrow
Keywords = gene expression profiling
Reference: Haematologica 2005;90:890-898
Keywords: ordered
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| Contributor(s) |
De Pittà C, Tombolan L, Campo Dell'Orto M, Accordi B, te Kronnie G, Romualdi C, Vitulo N, Basso G, Lanfranchi G |
| Citation(s) |
15996926 |
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| Submission date |
May 03, 2005 |
| Last update date |
Jul 26, 2013 |
| Contact name |
Gerolamo Lanfranchi |
| E-mail(s) |
stefano.cagnin@unipd.it
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| Phone |
+39-0498276219
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| Organization name |
University of Padova
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| Department |
CRIBI - Biotechnology Center and Biology Department
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| Lab |
Functional Genomics Lab
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| Street address |
Via U. Bassi, 58/B
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| City |
Padova |
| ZIP/Postal code |
35131 |
| Country |
Italy |
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| Platforms (1) |
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| Samples (36)
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| GSM49966 |
Gene expression profiling of patient No. 1 (A) |
| GSM49967 |
Gene expression profiling of patient No. 1 (B) |
| GSM49969 |
Gene expression profiling of patient No. 2 (A) |
| GSM49970 |
Gene expression profiling of patient No. 2 (B) |
| GSM49971 |
Gene expression profiling of patient No. 3 (A) |
| GSM49972 |
Gene expression profiling of patient No. 3 (B) |
| GSM49973 |
Gene expression profiling of patient No. 4 (A) |
| GSM49974 |
Gene expression profiling of patient No. 4 (B) |
| GSM49976 |
Gene expression profiling of patient No. 5 (A) |
| GSM49977 |
Gene expression profiling of patient No. 5 (B) |
| GSM49978 |
Gene expression profiling of patient No. 6 (A) |
| GSM49979 |
Gene expression profiling of patient No. 6 (B) |
| GSM49980 |
Gene expression profiling of patient No. 7 (A) |
| GSM49981 |
Gene expression profiling of patient No. 7 (B) |
| GSM49982 |
Gene expression profiling of patient No. 8 (A) |
| GSM49983 |
Gene expression profiling of patient No. 8 (B) |
| GSM49984 |
Gene expression profiling of patient No. 9 (A) |
| GSM49985 |
Gene expression profiling of patient No. 9 (B) |
| GSM49986 |
Gene expression profiling of patient No. 10 (A) |
| GSM49987 |
Gene expression profiling of patient No. 10 (B) |
| GSM49988 |
Gene expression profiling of patient No. 11 (A) |
| GSM49989 |
Gene expression profiling of patient No. 11 (B) |
| GSM49990 |
Gene expression profiling of patient No. 12 (A) |
| GSM49991 |
Gene expression profiling of patient No. 12 (B) |
| GSM49992 |
Gene expression profiling of patient No. 13 (A) |
| GSM49993 |
Gene expression profiling of patient No. 13 (B) |
| GSM49994 |
Gene expression profiling of patient No. 14 (A) |
| GSM49995 |
Gene expression profiling of patient No. 14 (B) |
| GSM49996 |
Gene expression profiling of patient No. 15 (A) |
| GSM49997 |
Gene expression profiling of patient No. 15 (B) |
| GSM49999 |
Gene expression profiling of patient No. 16 (A) |
| GSM50001 |
Gene expression profiling of patient No. 16 (B) |
| GSM50004 |
Gene expression profiling of patient No. 17 (A) |
| GSM50005 |
Gene expression profiling of patient No. 17 (B) |
| GSM50006 |
Gene expression profiling of patient No. 18 (A) |
| GSM50007 |
Gene expression profiling of patient No. 18 (B) |
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| Relations |
| BioProject |
PRJNA92021 |
| Supplementary data files not provided |
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